Introduction: Kidney dysfunction poses a high burden on patients and health care systems.
Early detection and accurate prediction of kidney disease progression remains a major …

Precision medicine is since long an ongoing refinement of classical medicine, integrating
improved and more detailed pathophysiological understanding with rapid technological …

Urine is a biological material that can be easily obtained in the clinic. The identification of
proteins excreted in urine provides useful biological information about the kidney as well as …

There is intense interest in applying proteomics to urine analysis in order to promote a better
understanding of kidney disease processes, develop new biomarkers for diagnosis and …

Renal biopsy remains the gold standard test for definitive diagnosis of glomerular diseases.
This invasive procedure; however, has a potential risk for serious complications and is …

The strong need for the discovery of novel disease markers together with the development of
high-throughput techniques that provide highly sensitive analysis of protein content in …

A major challenge in clinical proteomics is the identification of reliable biomarkers that help
early diagnosis of disease, which will not only assist the clinician but also contribute to the …

Chronic kidney disease accounts for a significant portion of many national health‐care
budgets. In this viewpoint, we highlight recent advances in urinary proteomic analyses that …

ical proteomics. Applications of renal and urinary proteomics have the ultimate goals of
better understanding of renal (patho) physiology, identification of new therapeutic targets …

Urinary differential proteomics is used to study renal pathophysiological mechanisms, find
novel markers of biological processes and renal diseases, and stratify patients according to …