Amorphous solid dispersions (ASDs), where an active pharmaceutical ingredient (API) is
dissolved in a polymer, are a favored formulation technique to achieve sufficient …

In formulation development, amorphous solid dispersions (ASD) are considered to improve
the bioavailability of poorly water-soluble active pharmaceutical ingredients (APIs) …

Amorphous solid dispersions (ASDs) are a widely used formulation technology for poorly
water-soluble active pharmaceutical ingredients (API). Depending on the API-polymer …

Amorphous solid dispersions (ASDs) of a poorly water-soluble active pharmaceutical
ingredient (API) in a polymer matrix can enhance the water solubility and therefore generally …

One way to increase the slow dissolution rate and the associated low bioavailability of newly
developed active pharmaceutical ingredients (APIs) is to dissolve the API in a polymer …

Amorphous solid dispersions (ASD) are intended to improve the bioavailability of poorly
water-soluble active pharmaceutical ingredients. However, the development of long-term …

Understanding the long-term stability of amorphous solid dispersions (ASDs) is important for
their successful approval for market. ASD stability does not only depend on the interplay …

The molecular integration of poorly water soluble active pharmaceutical ingredients (APIs) in
a suitable polymeric matrix is a possible approach to enhance the dissolution behavior and …

In this paper, we establish a mechanistic model for the prediction of amorphous solid
dispersion (ASD) stability. The novel approach incorporates fundamental physical …

The physical stability of amorphous solid dispersions (ASDs) is a major topic in the
formulation research of oral dosage forms. To minimize the effort of investigating the long …