Anti-infective potential of natural products: How to develop a stronger in vitro 'proof-of-concept'

P Cos, AJ Vlietinck, DV Berghe, L Maes - Journal of ethnopharmacology, 2006 - Elsevier
Natural products, either as pure compounds or as standardized plant extracts, provide
unlimited opportunities for new drug leads because of the unmatched availability of …

Antibacterial effects of flavonoids and their structure-activity relationship study: A comparative interpretation

NF Shamsudin, QU Ahmed, S Mahmood, SA Ali Shah… - Molecules, 2022 - mdpi.com
According to the latest report released by the World Health Organization, bacterial
resistance to well-known and widely available antibacterial drugs has become a significant …

Potential of selected African medicinal plants as alternative therapeutics against multi-drug-resistant bacteria

BN Moiketsi, KPP Makale, G Rantong, TO Rahube… - Biomedicines, 2023 - mdpi.com
Antimicrobial resistance is considered a “One-Health” problem, impacting humans, animals,
and the environment. The problem of the rapid development and spread of bacteria resistant …

Antibacterial activity of flavonoids and their structure–activity relationship: An update review

F Farhadi, B Khameneh, M Iranshahi… - Phytotherapy …, 2019 - Wiley Online Library
Based on World Health Organization reports, resistance of bacteria to well‐known antibiotics
is a major global health challenge now and in the future. Different strategies have been …

Antimicrobial natural products: an update on future antibiotic drug candidates

M Saleem, M Nazir, MS Ali, H Hussain, YS Lee… - Natural product …, 2010 - pubs.rsc.org
Covering: 2000 to 2008 Over the last decade, it has become clear that antimicrobial drugs
are losing their effectiveness due to the evolution of pathogen resistance. There is therefore …

[HTML][HTML] Developing new antimicrobial therapies: are synergistic combinations of plant extracts/compounds with conventional antibiotics the solution?

MJ Cheesman, A Ilanko, B Blonk… - Pharmacognosy reviews, 2017 - ncbi.nlm.nih.gov
The discovery of penicillin nearly 90 years ago revolutionized the treatment of bacterial
disease. Since that time, numerous other antibiotics have been discovered from bacteria …

Interactions between medical plant-derived bioactive compounds: focus on antimicrobial combination effects

N Vaou, E Stavropoulou, C Voidarou, Z Tsakris… - Antibiotics, 2022 - mdpi.com
It is accepted that the medicinal use of complex mixtures of plant-derived bioactive
compounds is more effective than purified bioactive compounds due to beneficial …

Synergism between natural products and antibiotics against infectious diseases

S Hemaiswarya, AK Kruthiventi, M Doble - Phytomedicine, 2008 - Elsevier
Antibiotics have been effective in treating infectious diseases, but resistance to these drugs
has led to the emergence of new and the reemergence of old infectious diseases. One …

Multifunctional therapeutic potential of phytocomplexes and natural extracts for antimicrobial properties

MM Rahman, MS Rahaman, MR Islam, ME Hossain… - Antibiotics, 2021 - mdpi.com
Natural products have been known for their antimicrobial factors since time immemorial.
Infectious diseases are a worldwide burden that have been deteriorating because of the …

Opportunities for plant natural products in infection control

AM Salam, CL Quave - Current opinion in microbiology, 2018 - Elsevier
The continued spread of antimicrobial resistance represents one of the most serious
infectious disease threats to global health. There is consensus that a key component of …