Cellular communication mediated by gap junction channels and hemichannels, both
composed of connexin proteins, constitutes two acknowledged regulatory platforms in the …

Graphical abstract Gap junctions mediate cellular communication and homeostasis by
controlling the intercellular exchange of small and hydrophilic molecules and ions. Gap …

Connexins, a family of transmembrane proteins, are components of both gap junction
channels and hemichannels, which mediate the exchange of ions and small molecules …

Connexins constitute a large family of trans-membrane proteins that allow intercellular
communication and the transfer of ions and small signaling molecules between cells …

Connexins have been known to be the protein building blocks of gap junctions and mediate
cell–cell communication. In contrast to the conventional dogma, recent evidence suggests …

Direct communication between cells, mediated by gap junctions, is nowadays considered as
an indispensable mechanism in the maintenance of cellular homeostasis. In fact, gap …

Gap junctions, specialised membrane structures that mediate cell-to-cell communication in
almost all tissues, are composed of channel-forming integral membrane proteins termed …

Over 35 years ago the cell biology community was introduced to connexins as the subunit
employed to assemble semicrystalline clusters of intercellular channels that had been well …

The importance of intercellular communication to complex cellular processes such as
development, differentiation, growth, propagation of electrical impulses and diffusional …

Gap junctions (GJs) are the only known cellular structures that allow a direct transfer of
signaling molecules from cell-to-cell by forming hydrophilic channels that bridge the …