PET studies in dementia

K Herholz - Annals of nuclear medicine, 2003 - Springer
Measurement of local cerebral glucose metabolism (lCMRGlc) by positron emission
tomography (PET) and 18 F-2-fluoro-2-deoxy-d-glucose (FDG) has become a standard …

Comparison of 18F-FDG and PiB PET in cognitive impairment

VJ Lowe, BJ Kemp, CR Jack, M Senjem… - Journal of Nuclear …, 2009 - Soc Nuclear Med
The purpose of this study was to compare the diagnostic accuracy of glucose metabolism
and amyloid deposition as demonstrated by 18F-FDG and Pittsburg Compound B (PiB) PET …

Positron emission tomography and magnetic resonance imaging in the diagnosis and prediction of dementia

W Jagust - Alzheimer's & dementia, 2006 - Elsevier
BACKGROUND: The diagnosis of dementia, along with the prediction of who will develop
dementia, has been assisted by the development of the brain imaging techniques of …

What does fluorodeoxyglucose PET imaging add to a clinical diagnosis of dementia?

W Jagust, B Reed, D Mungas, W Ellis, C Decarli - Neurology, 2007 - AAN Enterprises
Background: Few studies have compared the accuracy of [18F] fluorodeoxyglucose (FDG)
PET to the accuracy of clinical and pathologic diagnosis in dementia patients. Methods …

Brain fluorodeoxyglucose (FDG) PET in dementia

T Kato, Y Inui, A Nakamura, K Ito - Ageing research reviews, 2016 - Elsevier
The purpose of this article is to present a selective and concise summary of
fluorodeoxyglucose (FDG) positron emission tomography (PET) in dementia imaging. FDG …

18F-FDG PET and perfusion SPECT in the diagnosis of Alzheimer and Lewy body dementias

JT O'Brien, MJ Firbank, C Davison… - Journal of Nuclear …, 2014 - Soc Nuclear Med
Brain imaging with glucose (18F-FDG) PET or blood flow (hexamethylpropyleneamine
oxime) SPECT is widely used for the differential diagnosis of dementia, though direct …

FDG-PET changes in brain glucose metabolism from normal cognition to pathologically verified Alzheimer's disease

L Mosconi, R Mistur, R Switalski, WH Tsui… - European journal of …, 2009 - Springer
Purpose We report the first clinicopathological series of longitudinal FDG-PET scans in post-
mortem (PM) verified cognitively normal elderly (NL) followed to the onset of Alzheimer's …

Differential effects of global and cerebellar normalization on detection and differentiation of dementia in FDG-PET studies

J Dukart, K Mueller, A Horstmann, B Vogt, S Frisch… - Neuroimage, 2010 - Elsevier
FDG-PET ([18F] fluorodeoxyglucose positron emission tomography) is frequently used to
improve the differential diagnosis of dementia. However, a fundamental methodological …

Clinical value of neuroimaging in the diagnosis of dementia: sensitivity and specificity of regional cerebral metabolic and other parameters for early identification of …

DHS Silverman, GW Small, ME Phelps - Clinical Positron Imaging, 1999 - Elsevier
Dementing illnesses such as Alzheimer's disease (AD) progressively devastate human brain
tissue and consequently the health and lives of people afflicted by these disorders. One of …

Brain 18F-FDG PET in the diagnosis of neurodegenerative dementias: comparison with perfusion SPECT and with clinical evaluations lacking nuclear imaging

DHS Silverman - Journal of Nuclear Medicine, 2004 - Soc Nuclear Med
The clinical identification and differential diagnosis of dementias is especially challenging in
the early stages, but the need for early, accurate diagnosis has become more important, now …