Multiple sclerosis (MS) is a complex polygenic disease in which gene-environment
interactions are important. A number of studies have investigated the association between …

The association between multiple sclerosis (MS) and tumor necrosis factor-alpha gene (TNF-
α) polymorphisms has been analyzed in several studies, but conflicting results have been …

Background: Environmental and genetic factors are thought to be involved in the
pathogenesis of multiple sclerosis (MS). Polymorphisms of tumor necrosis factor (TNF)-α …

Background: Multiple sclerosis (MS) is an immune-mediated disease of polygenic etiology.
Tumor necrosis factor-α (TNF-α) microsatellite as a proinflammatory cytokine is believed to …

Previous findings regarding the role of TNF-α-308 gene polymorphism in multiple sclerosis
(MS) are contradictory. The aim of this study was to investigate the possible influence of TNF …

Dysregulation in the expression of pro‐and anti‐inflammatory cytokines is one of the
milestones in multiple sclerosis (MS) development and progression. Tumour necrosis factor …

Objective–To investigate the association between tumor necrosis factor‐α (TNF‐α) G‐308A,
tumor necrosis factor‐β (TNF‐β) G+ 252A and interleukin‐4 (IL‐4) C‐590T polymorphisms …

ABSTRACT TNF-α is an important cytokine of the inflammatory response involved in the
pathogenesis of relapsing-remitting multiple sclerosis (RRMS). The aim of this study is to …

Tumor necrosis factor alpha, a proinflammatory cytokine, plays an important role in the
clinical activity of relapsing–remitting multiple sclerosis and the development of progression …

Tumor necrosis factor (TNF) α has been considered the prototypic cytopathogenic cytokine
in multiple sclerosis (MS), but recently this cytokine has been shown to possess significant …