Opioids are routinely used in the management of moderate to severe pain. However, in the
acute care setting, consistently undertreated and suboptimally managed pain continues to …

Opioid analgesics are drugs that bind to opioid receptors and share properties of the
naturally occurring endogenous opioids. The term narcotic is derived from the Greek word …

Opioids represent a class of analgesics that provide powerful dose—dependent pain relief
for patients suffering moderate to severe pain. The class includes a large number of …

Objectives: The objectives of this study were:(i) to determine the adverse‐effects profile of a
nurse‐managed, titrated intravenous analgesia protocol; and (ii) to characterize the use of …

This is an article in the Core Entrustables in Clinical Pharmacology series that describes
opioid therapy in acute and chronic pain. Opioid use during surgical procedures or …

Opioid medication is the first-line treatment for severe acute pain. Traditional methods of
opioid administration remain in common use today (oral, rectal, intramuscular injection …

Acute pain is common and occurs most often in the immediate postoperative period. Acute
nonsurgical pain related to burns injury, trauma, sickle cell crisis, ureteric colic, and acute …

Study objective We assess the effectiveness of patient-controlled analgesia in the
emergency department (ED). We hypothesized that decline in pain intensity from 30 to 120 …

OBJECTIVES: Pain management in emergency department (ED) patients is variable and
often inadequate. This study sought to (1) describe the variability in intravenous opioid …

This chapter discusses the specifics about major opioids (meperidine, morphine,
oxycodone, oxymorphone, hydromorphone, methadone, buprenorphine, fentanyl, sufentanil …