Mesenchymal stromal cells are readily recoverable from lung tissue, but not the alveolar space, in healthy humans
KA Sinclair, ST Yerkovich, T Chen, JL McQualter… - Stem Cells, 2016 - academic.oup.com
Stromal support is critical for lung homeostasis and the maintenance of an effective
epithelial barrier. Despite this, previous studies have found a positive association between …
epithelial barrier. Despite this, previous studies have found a positive association between …
Lung-resident mesenchymal stromal cells are tissue-specific regulators of lung homeostasis
SN Sveiven, TM Nordgren - American Journal of …, 2020 - journals.physiology.org
Until recently, data supporting the tissue-resident status of mesenchymal stromal cells
(MSC) has been ambiguous since their discovery in the 1950–60s. These progenitor cells …
(MSC) has been ambiguous since their discovery in the 1950–60s. These progenitor cells …
Primary mesenchymal stem cells in human transplanted lungs are CD90/CD105 perivascularly located tissue-resident cells
S Rolandsson, AA Sjöland, JC Brune… - BMJ open …, 2014 - bmjopenrespres.bmj.com
Background Mesenchymal stem cells (MSC) have not only been implicated in the
development of lung diseases, but they have also been proposed as a future cell-based …
development of lung diseases, but they have also been proposed as a future cell-based …
The role of lung resident mesenchymal stromal cells in the pathogenesis and repair of chronic lung disease
DF Doherty, L Roets, AD Krasnodembskaya - Stem Cells, 2023 - academic.oup.com
Mesenchymal stromal/stem cells are multipotent adult cells that can be extracted from
numerous tissues, including the lungs. Lung-resident MSCs (LR-MSCs) are localized to …
numerous tissues, including the lungs. Lung-resident MSCs (LR-MSCs) are localized to …
Abnormalities in reparative function of lung-derived mesenchymal stromal cells in emphysema
DMLW Kruk, M Wisman, HG Bruin… - … of Physiology-Lung …, 2021 - journals.physiology.org
Mesenchymal stromal cells (MSCs) may provide crucial support in the regeneration of
destructed alveolar tissue (emphysema) in chronic obstructive pulmonary disease (COPD) …
destructed alveolar tissue (emphysema) in chronic obstructive pulmonary disease (COPD) …
Comparison of epithelial differentiation and immune regulatory properties of mesenchymal stromal cells derived from human lung and bone marrow
Mesenchymal stromal cells (MSCs) reside in many organs including lung, as shown by their
isolation from fetal lung tissues, bronchial stromal compartment, bronchial-alveolar lavage …
isolation from fetal lung tissues, bronchial stromal compartment, bronchial-alveolar lavage …
Persistency of mesenchymal stromal/stem cells in lungs
E Ferrini, FF Stellari, V Franceschi, F Macchi… - Frontiers in cell and …, 2021 - frontiersin.org
Mesenchymal stromal/stem cells (MSCs) are a fibroblast-like cell population with high
regenerative potential that can be isolated from many different tissues. Several data suggest …
regenerative potential that can be isolated from many different tissues. Several data suggest …
Epithelial cell differentiation of human mesenchymal stromal cells in decellularized lung scaffolds
JJ Mendez, M Ghaedi, D Steinbacher… - … Engineering Part A, 2014 - liebertpub.com
Identification of appropriate donor cell types is important for lung cell therapy and for lung
regeneration. Previous studies have indicated that mesenchymal stromal cells derived from …
regeneration. Previous studies have indicated that mesenchymal stromal cells derived from …
Mesenchymal stem cells in chronic lung disease: culprit or savior?
M Pierro, B Thébaud - American Journal of Physiology …, 2010 - journals.physiology.org
CHRONIC LUNG DISEASES such as chronic obstructive pulmonary disease (COPD) and
emphysema are anticipated to become the third most common cause of death by 2030 (30) …
emphysema are anticipated to become the third most common cause of death by 2030 (30) …
Lung-derived mesenchymal stromal cell post-transplantation survival, persistence, paracrine expression, and repair of elastase-injured lung
AM Hoffman, JA Paxson, MR Mazan… - Stem cells and …, 2011 - liebertpub.com
While multipotent mesenchymal stromal cells have been recently isolated from adult lung (L-
MSCs), there is very limited data on their biological properties and therapeutic potential in …
MSCs), there is very limited data on their biological properties and therapeutic potential in …