Transport in the ER–Golgi shuttle is performed by COPII in the anterograde and by COPI in
the retrograde direction. How these transport steps are regulated and which mechanisms act …

The coat complex COPII forms vesicles at the endoplasmic reticulum to transport a variety of
cargo proteins to the Golgi structure. Recent biochemical and structural studies reveal the …

Cargo proteins exported from the endoplasmic reticulum to the Golgi apparatus are typically
transported in coat protein complex II (COPII)-coated vesicles of 60–90 nm diameter …

Coated vesicles transport proteins from the endoplasmic reticulum (ER) to the Golgi
apparatus. The formation of transport vesicles in vitro requires the incubation of an ER …

Protein trafficking from the endoplasmic reticulum (ER) to the Golgi apparatus involves
specific uptake into coat protein complex II (COPII)–coated vesicles of secretory and of …

Secretory proteins are transported to the Golgi complex in vesicles that bud from the
endoplasmic reticulum. The cytoplasmic coat protein complex II (COPII) is responsible for …

The conserved coat protein complex II (COPII) mediates the initial steps of secretory protein
trafficking by assembling onto subdomains of the endoplasmic reticulum (ER) in two layers …

Cellular versatility depends on accurate trafficking of diverse proteins to their organellar
destinations. For the secretory pathway (followed by approximately 30% of all proteins), the …

The COPII coat complex found on endoplasmic reticulum (ER)-derived vesicles plays a
critical role in cargo selection. We now address the potential role of biosynthetic cargo in …

The coat protein complex II (COPII) forms transport vesicles from the endoplasmic reticulum
and segregates biosynthetic cargo from ER-resident proteins. Recent high-resolution …