Systemic sclerosis (SSc) is a connective tissue disease characterized by widespread
vascular lesions and fibrosis of the skin and internal organs. In SSc, vasospasm causes …

Albumin is one of the most abundant proteins in the body of mammals: about 40% of its pool
is located in the intravascular space and the remainder is found in the interstitial space. The …

Myocardial ischemia is difficult to diagnose effectively with still few well-defined biochemical
markers for identification in advance, or in the absence of myocardial necrosis.“Ischemia …

Ischaemia occurs when there is a supply demand mismatch in cardiac blood flow. In
unstable angina, this occurs due to partial or total occlusion of a coronary artery due to …

Patients suffering from myocardial ischemia reportedly exhibit reduced in vitro binding of
exogenous Co2+ to the N‐terminal of human serum albumin (HSA). The purpose of our …

After reading this article, the reader should understand the current state of the albumin
cobalt binding test's ability to measure ischemia modified albumin and understand what …

OBJECTIVES:: There is concern that ischemia-modified albumin (IMA) levels measured by
albumin cobalt binding (ACB) assay reflect mainly albumin concentrations rather than …

Background: Clinical diagnoses were correlated with results of a Co (II)–albumin binding
assay in 167 patients treated at an emergency department of a health maintenance …

First identified in the early 1990s, IMA is produced when ischemia stresses released from
hypoxic heart tissue induce modification of circulating albumin. 5, 6 The amino terminal end …

Background: Ischemia-modified albumin (IMA) is a new marker of myocardial ischemia,
there is concern that IMA concentrations may be affected by ischemia occurring in tissues …