Background SARS-CoV-2 is an enveloped, positive-sense single-stranded RNA virus with a
30-kilobase genome, which, like all viruses, accumulates nucleotide mutations over time …

On January 10, 2020, the first genomic sequence of the severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2) isolated from a patient in Wuhan, China, was posted online. As …

In this issue of JAMA, Zhang and colleagues1 report the emergence of a novel severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2) variant in Southern California that …

The emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants
with concerning phenotypic mutations is of public health interest. Genomic surveillance is an …

CDC's genomic surveillance for SARS-CoV-2 variants generates population-based
estimates of the proportions of variants among all SARS-CoV-2 infections in the United …

On 26 January 2020, the first coronavirus disease 2019 (COVID-19) case was reported in
Arizona (third case in the United States)(1). Here, we report on early severe acute …

Early detection of emerging SARS-CoV-2 variants is critical to guiding rapid risk
assessments, providing clear and timely communication messages, and coordinating public …

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) genomic surveillance has
been vital in understanding the spread of coronavirus disease 2019 (COVID-19), the …

The current coronavirus disease 2019 (COVID-19) pandemic is the first to apply whole-
genome sequencing near to real time, with over 2 million severe acute respiratory syndrome …

Background COVID-19 has put enormous demand on laboratory infrastructure and required
an unprecedented rapid scale-up of testing capacity for its causative agent, SARS-CoV-2, at …