The kallikrein-kininogen-kinin system is an important vasodilator and vasodepressor
component of the cardiovascular system. Acting mainly through B2 receptors, kinins may …

Autocrine, paracrine, endocrine, and neuroendocrine hormonal systems help regulate
cardio‐vascular and renal function. Any change in the balance among these systems may …

Recent histochemical and other studies have revealed that renal kallikrein is localized in
cells in the connecting tubules of the nephron and that low molecular weight (LMW) …

Role of renal kallikrein–kinin system has been studied using mutant Brown-Norway
Katholiek (BN-Ka) rats, in which both high-and low-molecular weight kininogens were …

We investigated the status of circulating kinins in rats with severe hypertension caused by
drinking 1% NaCl (saline) and treatment with deoxycorticosterone (DOC, 25 mg/kg/wk sc) for …

Brown Norway kininogen-deficient rats had very low levels of plasma kininogens and lower
levels of plasma prekallikrein, compared with those of normal rats of the same strain …

On the basis of evidence suggesting the activation of the kallikrein-kinin system in steroid-
induced hypertension, we considered the possibility that the angiotensin-converting enzyme …

The blood pressure (BP)-lowering effect of the kallikrein-kinin system (KKS) has been
described for more than six decades (Frey, 1926). It is now widely believed that the KKS is …

1. The kallikrein-kinin system has a significant role in regulating arterial blood pressure. 2. 2.
Reduced formation of the kinin compontents may cause hypertensive diseases. This is …

The influence of endogenous bradykinin (BK) on the control of arterial pressure and the
development of cardiac hypertrophy was assessed in chronically angiotensin II (Ang II) …