Protease inhibitor resistance is uncommon in HIV‐1 subtype C infected patients on failing second‐line lopinavir/r‐containing antiretroviral therapy in South Africa

CL Wallis, JW Mellors, WDF Venter… - AIDS research and …, 2011 - Wiley Online Library
Limited data exist on HIV‐1 drug resistance patterns in South Africa following second‐line
protease‐inhibitor containing regimen failure. This study examined drug resistance patterns …

Prevalence of antiretroviral drug resistance in patients who are not responding to protease inhibitor–based treatment: results from the first national survey in South …

K Steegen, M Bronze… - The Journal of …, 2016 - academic.oup.com
Limited data exist on human immunodeficiency virus type 1 (HIV-1) resistance in patients
who are not responding to protease inhibitor (PI)–based regimens in resource-limited …

Virologic failure of protease inhibitor-based second-line antiretroviral therapy without resistance in a large HIV treatment program in South Africa

JH Levison, C Orrell, S Gallien, DR Kuritzkes, N Fu… - PloS one, 2012 - journals.plos.org
Background We investigated the prevalence of wild-type virus (no major drug resistance)
and drug resistance mutations at second-line antiretroviral treatment (ART) failure in a large …

Genotypic resistance profiles of HIV-2-treated patients in West Africa

C Charpentier, S Eholié, X Anglaret, M Bertine… - Aids, 2014 - journals.lww.com
Objective: To assess the virological response, genotypic resistance profiles, and
antiretroviral plasma concentrations in HIV-2 antiretroviral-treated (antiretroviral therapy …

Development and significance of resistance to protease inhibitors in HIV‐1‐infected adults under triple‐drug therapy in clinical practice

L Romano, G Venturi, S Giomi, L Pippi… - Journal of medical …, 2002 - Wiley Online Library
Abstract Development of drug resistance is considered a major cause for failure of
antiretroviral therapy in human immunodeficiency virus type 1 (HIV‐1)‐infected patients …

No increase in protease resistance and a decrease in reverse transcriptase resistance mutations in primary HIV-1 infection: 1992–2001

P Ammaranond, P Cunningham, R Oelrichs, K Suzuki… - Aids, 2003 - journals.lww.com
Rates of antiretroviral resistance in recently transmitted virus in Sydney, Australia fluctuated
over the past decade, influenced by treatment trends. Current rates of drug resistance are …

Prevalence of HIV-1 drug resistance after failure of a first highly active antiretroviral therapy regimen in KwaZulu Natal, South Africa

VC Marconi, H Sunpath, Z Lu, M Gordon… - Clinical infectious …, 2008 - academic.oup.com
Background. Emergence of human immunodeficiency virus type 1 (HIV-1) drug resistance
may limit the benefits of antiretroviral therapy in resource-limited settings. The prevalence of …

Antiretroviral drug susceptibility among HIV-infected adults failing antiretroviral therapy in Rakai, Uganda

SJ Reynolds, O Laeyendecker, G Nakigozi… - AIDS research and …, 2012 - liebertpub.com
We analyzed antiretroviral drug susceptibility in HIV-infected adults failing first-and second-
line antiretroviral treatment (ART) in Rakai, Uganda. Samples obtained from participants at …

Protease inhibitor resistance in the first 3 years of second-line antiretroviral therapy for HIV-1 in sub-Saharan Africa

TS Boender, RL Hamers, P Ondoa… - The Journal of …, 2016 - academic.oup.com
Background. As antiretroviral therapy (ART) programs in sub-Saharan Africa mature,
increasing numbers of persons with human immunodeficiency virus (HIV) infection will …

Resistance mutational analysis of HIV type 1 subtype C among rural South African drug-naive patients prior to large-scale availability of antiretrovirals

PO Bessong, J Mphahlele, IA Choge… - AIDS Research & …, 2006 - liebertpub.com
Baseline HIV-1 resistance data are important for resistance monitoring purposes especially
in regions initiating large-scale antiretroviral treatment programs. We examined 40 protease …