Metabolomic characterization of myocardial ischemia-reperfusion injury in ST-segment elevation myocardial infarction patients undergoing percutaneous coronary …

A Surendran, M Aliani, A Ravandi - Scientific reports, 2019 - nature.com
Aim: The aim of the study was to discover the metabolomic changes in plasma that occur
during human Ischemia-Reperfusion (I/R) injury and to evaluate the diagnostic utility of …

Serum Metabolomics Reveals Distinct Profiles during Ischemia and Reperfusion in a Porcine Model of Myocardial Ischemia–Reperfusion

E Goetzman, Z Gong, D Rajasundaram… - International Journal of …, 2022 - mdpi.com
Acute myocardial infarction (MI) is one of the leading causes of death worldwide. Early
identification of ischemia and establishing reperfusion remain cornerstones in the treatment …

Metabolomics study of the biochemical changes in the plasma of myocardial infarction patients

M Zhu, Y Han, Y Zhang, S Zhang, C Wei… - Frontiers in …, 2018 - frontiersin.org
Myocardial infarction (MI) is a common and multifactorial disease that has the highest
morbidity and mortality in the world. Although a number of physiological, pathological, and …

Metabolomics of early myocardial ischemia

RB Hasselbalch, JH Kristensen, N Strandkjær… - Metabolomics, 2023 - Springer
Introduction Diagnosing myocardial infarction is difficult during the initial phase. As, acute
myocardial ischemia is associated with changes in metabolic pathways, metabolomics may …

Metabolomic identification of novel biomarkers of myocardial ischemia

MS Sabatine, E Liu, DA Morrow, E Heller, R McCarroll… - Circulation, 2005 - Am Heart Assoc
Background—Recognition of myocardial ischemia is critical both for the diagnosis of
coronary artery disease and the selection and evaluation of therapy. Recent advances in …

Metabolic characterization of myocardial infarction using GC-MS-based tissue metabolomics

X Wang, D Wang, J Wu, X Yu, J Lv, J Kong… - International heart …, 2017 - jstage.jst.go.jp
Understanding the metabolic features of myocardial infarction (MI) is critical to its prevention
and treatment. Here, we aimed to characterize the metabolic features of early MI using a …

Metabolomics in the diagnosis of acute myocardial ischemia

V Bodi, VG Marrachelli, O Husser, FJ Chorro… - Journal of …, 2013 - Springer
Despite recent advances in the diagnosis of myocardial ischemia, its biochemical
identification in patients with acute chest pain is still a challenge, and alternative approaches …

Metabolomic profile of human myocardial ischemia by nuclear magnetic resonance spectroscopy of peripheral blood serum: a translational study based on transient …

V Bodi, J Sanchis, JM Morales, VG Marrachelli… - Journal of the American …, 2012 - jacc.org
Objectives: The aim of this study was to investigate the metabolomic profile of acute
myocardial ischemia (MIS) using nuclear magnetic resonance spectroscopy of peripheral …

Cross-comparative metabolomics reveal sex-age specific metabolic fingerprints and metabolic interactions in acute myocardial infarction

W Liu, L Zhang, X Shi, G Shen, J Feng - Free Radical Biology and …, 2022 - Elsevier
The elucidation of metabolic perturbations and gender-age-specific metabolic
characteristics associated with acute myocardial infarction (AMI) is essential for clinical risk …

Plasma metabolomics reveals a potential panel of biomarkers for early diagnosis in acute coronary syndrome

CM Laborde, L Mourino-Alvarez, M Posada-Ayala… - Metabolomics, 2014 - Springer
Discovery of new biomarkers is critical for early diagnosis of acute coronary syndrome
(ACS). Recent advances in metabolomic technologies have drastically enhanced the …