Objective This study sought to describe, the natural history of major depressive disorder in a
large group of nonclinical subjects. In particular, the analysis determined demographic and …

In a longitudinal study of 30 successfully treated unipolar depressed patients, the authors
evaluated number of depressive episodes, early onset of depression, and lifetime …

Background: The long-term course of depression in patients who present for treatment
carries prognostic and therapeutic implications. This study presents prospective data on the …

OBJECTIVE: The recurrence of an affective disorder in people who initially recover from
major depressive disorder was characterized by using the unique longitudinal prospective …

Risk of relapse into an affective episode was high in the months immediately after recovery
from a major depressive disorder (MDD) in 141 subjects with nonbipolar depression, without …

• The relatives, controls, and spouses of affectively ill probands underwent diagnostic
examinations on two occasions, 6 years apart. Of 965 subjects who had never been …

Method As part of a family study of probands with major affective disorders, raters assessed
3,119 first-degree relatives, spouses, and comparison subjects. When 2,237 (71.7%) of …

Objective This research examined demographic, clinical, and family factors in elderly
depressed patients in order to ascertain which ones were related to the patients' recovery …

A cross-sectional evaluation of 243 unipolar, nonpsychotic outpatients with major
depression was conducted. All subjects were diagnosed by RDC with SADS-L structured …

Many individuals who experience a major depressive episode will subsequently develop
recurrent episodes. Although numerous studies have investigated predictors of recurrent …