Objective The primary objective was to determine the association between beta-2
adrenergic receptor (ADRB2) gene polymorphism (rs1042713, c. 46A> G, p. Arg16Gly) and …

OBJECTIVE: Previous studies have indicated that β2-adrenergic receptor (ADRB2) genetic
polymorphism is related to the risk of asthma, but the results still have some controversy and …

Introduction: The β2-adrenergic receptor (β2AR or ADRβ2) is the target for β2-agonist drugs
used for bronchodilation in asthma and other respiratory diseases. The aim of this study was …

Background There are a number of candidate genes thought to play a role in the
development of asthma. Polymorphisms at amino acid positions 16 (arginine to glycine) and …

Inhaled β2-agonists are the most commonly used treatment for asthma. It has been
hypothesized that patients who exhibit functional polymorphic variants of the β2-adrenergic …

Background We have previously reported a relationship between increased airway
responsiveness (AR) in infancy and reduced childhood lung function. Objective The current …

Objective To determine whether genetic polymorphisms of beta2-adrenergic receptor gene
affect asthma susceptibility and play a role in disease regulation. Methods One hundred and …

Polymorphisms of ADRB2 are not major risk factors for the development of asthma. These
polymorphisms are likely to be important, however, in determining drug response. Future …

BACKGROUND: We previously reported that the β2-adrenergic receptor (ADRB2)
polymorphism had no effect on bronchial hyperresponsiveness (BHR) to methacholine in …

Polymorphism at position 16 of the β2-adrenoceptor alters receptor down-regulation in vitro.
Our aim was to compare the development of tolerance to (3-agonist in homozygous Gly-16 …