Background: Periodontitis is an inflammatory disease that results in bone resorption creating
bony defects, which may cause tooth loss. Various drugs have been studied using local …

Background: Chronic periodontitis (CP) is an inflammatory condition affecting tooth‐
supporting tissues and alveolar bone that surround the tooth, leading to formation of a …

Background: Simvastatin (SMV) is a specific competitive inhibitor of 3‐hydroxy‐2‐methyl‐
glutaryl coenzyme A reductase. Recently, it has been reported that statins promote bone …

Background Simvastatin (SMV) is a specific competitive inhibitor of 3‐hydroxy‐2‐methyl‐
glutaryl coenzyme A reductase. Statins have recently been shown to promote bone …

Background: Atorvastatin (ATV) is a specific competitive inhibitor of 3‐hydroxy‐2‐methyl‐
glutaryl coenzyme A reductase. Recently, statins have shown pleiotropic effects such as anti …

Background The aim of this study is to explore and compare the clinical efficacy of locally
delivered 1.2% Rosuvastatin (RSV) and 1% Metformin (MF) gel as an adjunct to scaling and …

Background: Statins (3‐hydroxy‐3‐methylglutaryl coenzyme A reductase inhibitors) are an
important group of hypolipidemic drugs that are able to modulate inflammation and alveolar …

Background: Simvastatin (SMV) assists in bone regeneration and has an anti‐inflammatory
effect when delivered or applied locally. The present clinical trial is designed to investigate …

Periodontitis is an inflammatory disease of the supporting tissues of the teeth, caused by a
group of specific microorganisms. Aggressive forms of periodontitis can be localized or …

Objectives The impact of simvastatin (SMV), a cholesterol lowering drug, on bone
metabolism appears to involve complex interaction with cholesterol metabolites, hormones …