Autophagy is a critical cellular process that generally protects cells and organisms from
harsh environment, including limitations in adenosine triphosphate (ATP) availability or a …

Most cancer cells predominantly produce energy by glycolysis, even in the presence of
adequate oxygen. Therefore, inhibition of glycolysis is a promising cancer treatment target …

When it comes to cancer initiation and progression, macroautophagy/autophagy seemingly
acts in a contradictory fashion, serving either as a suppressive factor that functions to protect …

Autophagy is a critical cellular process that generally protects cells and organisms from
stressors such as nutrient deprivation. In addition to its role in normal physiology, autophagy …

Tumorigenesis is often accompanied by metabolic changes that favor rapid energy
production and increased biosynthetic capabilities. These metabolic adaptations promote …

Autophagy is an intracellular catabolic process that degrades cytoplasmic components for
recycling in response to stressed conditions, such as nutrient deprivation. Dysregulation of …

Simple Summary The metabolism of carbohydrates and lipids is essential to meet the
diverse needs of cells. The autophagy cellular pathway is crucial for normal cellular function …

Autophagy, a lysosomal catabolic process, involves degradation of cellular materials,
protein aggregate, and dysfunctional organelles to maintain cellular homeostasis. Strikingly …

Modulation of autophagy as an anticancer strategy has been widely studied and evaluated
in several cell models. However, little attention has been paid to the metabolic changes that …

The metabolism of malignant cells is profoundly altered in order to maintain their survival
and proliferation in adverse microenvironmental conditions. Autophagy is an intracellular …