Mutations in the SLC26A4 gene at the DFNB4 locus are responsible for Pendred syndrome
and non-syndromic hereditary hearing loss (DFNB4). This study included 80 nuclear …

Objective: To determine the prevalence and types of SLC26A4 mutations and the relevant
phenotypes in a series of Iranian deaf patients. Design: A descriptive laboratory study. Study …

Objective Mutations in the SLC26A4 gene cause both Pendred syndrome and autosomal
recessive nonsyndromic hearing loss (ARNSHL) at the DFNB4 locus. The SLC26A4 …

Objectives The aim of this study was to detect the genetic cause of deafness in a large
Iranian family. Due to the importance of SLC26A4 in causing hearing loss, information about …

Pendred's syndrome (PDS) is an autosomal-recessive disorder characterized by
sensorineural hearing loss and goiter. PDS is caused by mutations of the SLC26A4 gene …

OBJECTIVE: Recessive mutations of the SLC26A4 (PDS) gene on chromosome 7q31 can
cause sensorineural hearing loss with goiter (Pendred syndrome) or non-syndromic …

Pendred syndrome (PS) and DFNB4, a non-syndromic sensorineural hearing loss with
enlargement of the vestibular aqueduct (EVA), are caused by mutations in the SLC26A4 …

OBJECTIVES: Mutations in the SLC26A4 gene (7q22. 3–7q31. 1) are considered one of the
most common causes of genetic hearing loss. There are two clinical forms related to these …

The SLC26A4 gene has been described as the second gene involved in most cases of
sensorineural non-syndromic hearing loss, since the first is the GJB2 gene. Recessive …

Mutations in the SLC26A4 gene, which encodes pendrin, cause congenital hearing loss as
a manifestation of Pendred syndrome (PS) with an iodide organification defect or …