Background and Design of the US Study to Protect Brain Health through Lifestyle Intervention to Reduce Risk (US POINTER)

LD Baker, HM Snyder, MA Espeland… - Alzheimer's & …, 2023 - Wiley Online Library
Background US POINTER is a Phase 3, multicenter, randomized 2‐year clinical trial of two
multidomain lifestyle interventions in 2111 older adults who are at increased risk of cognitive …

Study design and methods: US study to protect brain health through lifestyle intervention to reduce risk (US POINTER)

LD Baker, HM Snyder, MA Espeland… - Alzheimer's & …, 2024 - Wiley Online Library
INTRODUCTION The US study to pr o tect brain health through lifestyle inte rvention to r
educe risk (US POINTER) is conducted to confirm and expand the results of the Finnish …

US Study to Protect Brain Health Through Lifestyle Intervention to Reduce Risk (US POINTER): Baseline Characteristics of a Trial Cohort Enriched for Risk of …

RA Whitmer - Alzheimer's & Dementia, 2023 - Wiley Online Library
Background US POINTER is a two‐year clinical trial to evaluate whether lifestyle
interventions targeting multiple risk factors protect cognitive function in older adults at …

[引用][C] O4‐11‐03: US Pointer: Study design and launch

LD Baker, DP Beavers, MJ Cleveland… - Alzheimer's & …, 2019 - Wiley Online Library
Background There is an urgent need to expand the Finnish Geriatric Intervention Study to
Prevent Cognitive Impairment and Disability (FINGER) results in geographically and …

[HTML][HTML] The design and progress of a multidomain lifestyle intervention to improve brain health in middle-aged persons to reduce later Alzheimer's disease risk: The …

MC Norton, CJ Clark, JAT Tschanz, P Hartin… - Alzheimer's & Dementia …, 2015 - Elsevier
Abstract Introduction Most Alzheimer's disease (AD) prevention studies focus on older adults
or persons with existing cognitive impairment. This study describes the design and progress …

US POINTER (USA) World‐wide FINGERS network: the first global network of multidomain dementia prevention trials

LD Baker, MA Espeland, M Kivipelto… - Alzheimer's & …, 2020 - Wiley Online Library
Background US POINTER aims to test whether a multidomain lifestyle intervention focused
on physical and cognitive activity, nutrition, and risk factor management reduces risk of …

LatAm‐FINGERS and US POINTER: Design and Cohort Characteristics of Parallel Harmonized Trials of Multidomain Lifestyle Interventions Targeting Cognition

CK Suemoto, RF Allegri, LD Baker… - Alzheimer's & …, 2023 - Wiley Online Library
Background Multidomain lifestyle interventions hold great promise world‐wide as
interventions to slow cognitive aging, and delay and prevent Alzheimer's Disease and …

NeuroVoices: Miia Kivipelto, MD, PhD, on Using Multidomain Interventions to Prevent Cognitive Decline.

M Meglio - Neurology Times, 2022 - go.gale.com
In recent years, there has been an accumulating amount of evidence to suggest that there
are several potentially modifiable risk factors that attribute to the development of Alzheimer …

US POINTER: lessons learned about delivery of a multi‐domain lifestyle intervention during the COVID‐19 pandemic

LD Baker, MA Espeland, RA Whitmer… - Alzheimer's & …, 2021 - Wiley Online Library
Background US POINTER is testing whether multidomain lifestyle interventions focused on
physical exercise, nutrition, cognitive challenge, and risk factor management reduces risk of …

[引用][C] Advanced Clinical Research in Lifestyle Interventions

H Eating, NIA Blog-Inside - nia.nih.gov
More scientific evidence is still needed, but strategies are emerging to potentially reduce
dementia risk or delay its onset and progression. A 2017 evidence-based, NIA …