Fibrosis is a general term to describe diseases that lead to an increase of connective tissue.
This may lead to tissue remodelling, formation of permanent scar tissue and changes in the …

Lung diseases such as fibrosis, asthma, cystic fibrosis, infection and cancer are life-
threatening conditions that slowly deteriorate quality of life and for which our diagnostic …

Pulmonary fibrosis (PF) is a severe and progressive condition in which the lung becomes
scarred over time resulting in pulmonary function impairment. Classical histopathology …

Sustained injury from factors such as hypoxia, infection, or physical damage may provoke
improper tissue repair and the anomalous deposition of connective tissue that causes …

Assessing alterations of the parenchymal architecture is essential in understanding fibrosing
interstitial lung diseases. Here, we present a novel method to visualise fibrotic remodelling …

Pulmonary fibrosis is the replacement of healthy tissue by an excessive deposition of
extracellular matrix components leading to an irreversible destruction of the lung …

Small animal models of lung fibrosis are essential for unraveling the molecular mechanisms
underlying human fibrotic lung diseases; additionally, they are useful for preclinical testing of …

Respiratory ailments continue to pose a formidable challenge to public health. The
respiratory system is a delicate interplay of muscle contraction, pressure gradients and a …

The architectural complexity of the lung is crucial to its ability to function as an organ of gas
exchange; the branching tree structure of the airways transforms the tracheal cross-section …

Rationale: Pulmonary fibrosis (PF) represents a common pathological outcome of multiple
diseases that affects> 3,000,000 patients. Few studies to date have analyzed lung tissue at …