Curcumin induces pancreatic adenocarcinoma cell death via reduction of the inhibitors of apoptosis

CJD Osterman, A Gonda, TR Stiff, U Sigaran… - Pancreas, 2016 - journals.lww.com
Objectives The inhibitor of apoptosis (IAP) proteins are critical modulators of
chemotherapeutic resistance in various cancers. To address the alarming emergence of …

Development of curcumin as an epigenetic agent

S Fu, R Kurzrock - Cancer, 2010 - Wiley Online Library
The clinical benefits of curcumin as a single agent were demonstrated in patients with
advanced pancreatic cancer in a phase 2 study despite pharmacokinetic analysis showing a …

Curcumin: a wonder anticancer drug.

YP Palve, PL Nayak - 2012 - cabidigitallibrary.org
Abstract Curcumin [(1E, 6E)-1, 7-bis (4-hydroxy-3-methoxyphenyl) hepta-1, 6-diene-3, 5di
one] is the major yellow pigment extracted from turmeric, a commonly used spice, derived …

Multi‐targeted therapy by curcumin: how spicy is it?

A Goel, S Jhurani, BB Aggarwal - Molecular Nutrition & Food …, 2008 - Wiley Online Library
Although traditional medicines have been used for thousands of years, for most such
medicines neither the active component nor their molecular targets have been very well …

Curcumin in clinical practice: myth or reality?

C Mancuso, E Barone - Trends in Pharmacological Sciences, 2009 - cell.com
In the interesting paper 'Pharmacological basis for the role of curcumin in chronic diseases:
an age-old spice with modern targets' published in the February issue of Trends in …

[HTML][HTML] Antimetastatic effects of curcumin in oral and gastrointestinal cancers

A Davoodvandi, M Farshadi, N Zare… - Frontiers in …, 2021 - frontiersin.org
Gastrointestinal (GI) cancers are known as frequently occurred solid malignant tumors that
can cause the high rate mortality in the world. Metastasis is a significant destructive feature …

[HTML][HTML] Clinical effects of curcumin in enhancing cancer therapy: A systematic review

K Mansouri, S Rasoulpoor, A Daneshkhah, S Abolfathi… - BMC cancer, 2020 - Springer
Background Curcumin is herbal compound that has been shown to have anti-cancer effects
in pre-clinical and clinical studies. The anti-cancer effects of curcumin include inhibiting the …

Comparison of the effects of curcumin and curcumin glucuronide in human hepatocellular carcinoma HepG2 cells

M Shoji, K Nakagawa, A Watanabe, T Tsuduki… - Food chemistry, 2014 - Elsevier
Curcumin is a yellow pigment found in turmeric (Curcuma Longa L.), and is reported, in
recent studies, to have several pharmacological effects, including anti-oxidant, anti …

Curcumin and its formulations: potential anti-cancer agents

JL Ji, XF Huang, HL Zhu - Anti-Cancer Agents in Medicinal …, 2012 - ingentaconnect.com
Curcumin, one of the most studied chemopreventive agents, is a natural compound
extracted from Curcuma longa L. Extensive research over the last half century has revealed …

[HTML][HTML] The golden spice curcumin in cancer: A perspective on finalized clinical trials during the last 10 years

AKK Arslan, E Uzunhisarcıklı, MB Yerer… - Journal of Cancer …, 2022 - journals.lww.com
Curcumin, the key bioactive phytochemical present in turmeric (Curcuma longa L.), is the
most studied natural compound in cancer. Preclinical studies (in vitro and in vitro) and …