Allicin mitigates hepatic injury following cyclophosphamide administration via activation of Nrf2/ARE pathways and through inhibition of inflammatory and apoptotic …
D Sun, C Sun, G Qiu, L Yao, J Yu, H Al Sberi… - … Science and Pollution …, 2021 - Springer
Abstract Treatment with anti-neoplastic agents, including cyclophosphamide (CP), is
associated with several adverse reactions. Here, we distinguished the potential protective …
associated with several adverse reactions. Here, we distinguished the potential protective …
Hepatoprotective effect of allicin against acetaminophen‐induced liver injury: Role of inflammasome pathway, apoptosis, and liver regeneration
Acetaminophen (APAP) overdose leads to liver injury. NLRP3 inflammasome is a key player
in APAP‐induced inflammation. Also, apoptosis and liver regeneration play an important …
in APAP‐induced inflammation. Also, apoptosis and liver regeneration play an important …
[PDF][PDF] Upregulation of Nrf2/HO-1 signaling and attenuation of oxidative stress, inflammation, and cell death mediate the protective effect of apigenin against …
Liver injury is among the adverse effects of the chemotherapeutic agent cyclophosphamide
(CP). This study investigated the protective role of the flavone apigenin (API) against CP …
(CP). This study investigated the protective role of the flavone apigenin (API) against CP …
[HTML][HTML] Upregulation of Nrf2/HO-1 signaling and attenuation of oxidative stress, inflammation, and cell death mediate the protective effect of apigenin against …
Liver injury is among the adverse effects of the chemotherapeutic agent cyclophosphamide
(CP). This study investigated the protective role of the flavone apigenin (API) against CP …
(CP). This study investigated the protective role of the flavone apigenin (API) against CP …
[HTML][HTML] Galangin activates Nrf2 signaling and attenuates oxidative damage, inflammation, and apoptosis in a rat model of cyclophosphamide-induced hepatotoxicity
Cyclophosphamide (CP) is a widely used chemotherapeutic agent; however, its clinical
application is limited because of its multi-organ toxicity. Galangin (Gal) is a bioactive …
application is limited because of its multi-organ toxicity. Galangin (Gal) is a bioactive …
Allicin alleviated acrylamide-induced NLRP3 inflammasome activation via oxidative stress and endoplasmic reticulum stress in Kupffer cells and SD rats liver
B Nan, C Yang, L Li, H Ye, H Yan, M Wang… - Food and Chemical …, 2021 - Elsevier
Acrylamide (AA) in heat-processed food leads to widespread concerns due to its
hepatotoxicity. Allicin, a plant-derived antioxidant, possesses a significant protective effect …
hepatotoxicity. Allicin, a plant-derived antioxidant, possesses a significant protective effect …
Allicin modulates diclofenac sodium induced hepatonephro toxicity in rats via reducing oxidative stress and caspase 3 protein expression
Purpose This study was designed to evaluate the protective effects of allicin against
diclofenac sodium induced hepatonephro toxicity in rats. Methods Sixty male Wister albino …
diclofenac sodium induced hepatonephro toxicity in rats. Methods Sixty male Wister albino …
[HTML][HTML] Role of NADPH Oxidase-Derived ROS-Mediated IL-6/STAT3 and MAPK/NF-κB Signaling Pathways in Protective Effect of Corilagin against Acetaminophen …
FC Liu, HC Lee, CC Liao, AH Chou, HP Yu - Biology, 2023 - mdpi.com
Simple Summary Acetaminophen overdose causes acute liver injury by excessive oxidative
stress. The present study examines the mechanisms underlying the protective effect of …
stress. The present study examines the mechanisms underlying the protective effect of …
Activation of the Nrf2 signaling pathway involving KLF9 plays a critical role in allicin resisting against arsenic trioxide-induced hepatotoxicity in rats
D Yang, Z Lv, H Zhang, B Liu, H Jiang, X Tan… - Biological trace element …, 2017 - Springer
Abstract Arsenic trioxide (As 2 O 3) is both the most prevalent, naturally occurring inorganic
arsenical threatening human health and an efficient therapeutic for acute promyelocytic …
arsenical threatening human health and an efficient therapeutic for acute promyelocytic …
Apigenin inhibits d-galactosamine/LPS-induced liver injury through upregulation of hepatic Nrf-2 and PPARγ expressions in mice
RJ Zhou, H Ye, F Wang, JL Wang, ML Xie - Biochemical and biophysical …, 2017 - Elsevier
Apigenin is a natural flavonoid compound widely distributed in a variety of vegetables,
medicinal plants and health foods. This study aimed to examine the protective effect of …
medicinal plants and health foods. This study aimed to examine the protective effect of …