Inflammation and oxidative stress serve an important role in the development of
lipopolysaccharide/D-galactosamine (LPS/GalN)‑induced acute liver injury. Nobiletin, which …

Cyclophosphamide (CP)‐induced hepatotoxic manifestations are major concern for patients
undergoing chemotherapy, which often limit its therapeutic utility. Nerolidol (NER) is a …

Overuse of acetaminophen (APAP) is a major cause of drug-induced liver failure at the
clinics. Apigenin (API) is a natural flavonoid derived from Matricaria chamomilla. The aim of …

Liver damage and fibrosis are serious health problems without effective treatment.
Proanthocyanidins (PAs) are flavonoids with several biological effects. We investigated the …

Septic liver injury/failure that is mainly characterized by oxidative stress, inflammation, and
apoptosis led to a great part of terminal liver pathology with limited effective intervention …

Overdose of N-acetyl-para-aminophenol (APAP) can induce acute liver injury (ALI). We
evaluated the potential protective effect of 8-methyl-N-geranyl-6-nonamide (capsaicin …

Chronic tobacco use can lead to liver damage and inflammation due to the accumulation of
various toxins in the body. This study aimed to investigate the correlation between the …

Overdose of acetaminophen (APAP) is the main reason for acute liver failure. Oxidative
stress is associated with hepatotoxicity caused by APAP. Betaine is a methyl donor and S …

Liver regeneration has become a new hotspot in the study of drug-induced liver injury (DILI).
Baicalin has already been reported to alleviate acetaminophen (APAP)-induced acute liver …

Acrylamide (ACR) is a heat-induced carcinogen substance that is found in some foods due
to cooking or other thermal processes. The aim of present study was to assess the probable …