[HTML][HTML] High Expression of Inflammatory Cytokines and Chemokines in Human T-lymphotropic Virus 1-Associated Adult T-cell Leukemia/Lymphoma

S Soltani, SH Mozhgani, G Siri, MS Emadi… - Jundishapur Journal of …, 2022 - brieflands.com
Background: Human T-cell lymphotropic virus type 1 (HTLV-1) is the etiological agent of
adult T-cell leukemia/lymphoma (ATLL) without any specific antiviral. Objectives: This study …

Frequent activating somatic alterations in T-cell receptor/NF-κb signaling in adult T-cell leukemia/lymphoma

K Kataoka, Y Nagata, A Kitanaka, Y Shiraishi… - 2015 - ashpublications.org
Adult T-cell leukemia/lymphoma (ATL) is a peripheral T-cell neoplasm of largely unknown
genetic basis, which is associated with human T-cell leukemia virus type-1 (HTLV-1) …

[HTML][HTML] A Comprehensive study of the immunophenotype and its clinicopathologic significance in adult T-Cell leukemia/lymphoma

T Tamaki, K Karube, S Sakihama, Y Tsuruta… - Modern Pathology, 2023 - Elsevier
Adult T-cell leukemia/lymphoma (ATLL) is a mature T-cell tumor caused by human T-
lymphotropic virus type 1 (HTLV-1). The typical ATLL immunophenotypes are described in …

[HTML][HTML] Altered expression of cell cycle regulators in adult T-cell leukemia/lymphoma patients

R Torshizi, EG Karimani, K Etminani… - … of biochemistry & …, 2017 - ncbi.nlm.nih.gov
Background: Adult T-cell leukemia/lymphoma (ATLL) is caused by human T-cell
lymphotropic virus type-1 (HTLV-1). HTLV-1 oncogenes can induce malignancy through …

Assessment of HTLV-1 proviral load, LAT, BIM, c-FOS and RAD51 gene expression in adult T cell leukemia/lymphoma

S Ramezani, A Shirdel, H Rafatpanah… - Medical microbiology …, 2017 - Springer
Adult T cell leukemia/lymphoma (ATLL) is a life-threatening malignancy of HTLV-1 infected
Th lymphocytes. In the present study host–virus interactions were investigated by …

Proteomic profiling of HTLV-1 carriers and ATL patients reveals sTNFR2 as a novel diagnostic biomarker for acute ATL

CLH Guerrero, Y Yamashita, M Miyara… - Blood …, 2020 - ashpublications.org
Adult T-cell leukemia/lymphoma (ATL) is a human T-cell leukemia virus type 1 (HTLV-1)–
associated T-cell malignancy with generally poor prognosis. Although only∼ 5% of HTLV-1 …

Genetic landscape of adult T-cell leukemia/lymphoma

K Kataoka, S Ogawa - [Rinsho Ketsueki] The Japanese Journal of …, 2016 - europepmc.org
Adult T-cell leukemia/lymphoma (ATL) is a peripheral T-cell malignancy associated with
HTLV-1 infection. To decipher the genetic landscape of ATL, we performed an integrated …

[HTML][HTML] The mirror like expression of genes involved in the FOXO signaling pathway could be effective in the pathogenesis of human lymphotropic virus type 1 (HTLV …

S Yaslianifard, M Movahedi, S Yaslianifard… - BMC Research …, 2023 - Springer
Objectives Human lymphotropic virus type 1 (HTLV-1) is the cause of two major diseases,
ATLL and HAM/TSP in a percentage of carriers. Despite progress in understanding the …

[HTML][HTML] IL-2/IL-2 receptor pathway plays a crucial role in the growth and malignant transformation of HTLV-1-infected T cells to develop adult T-cell leukemia

M Maeda, J Tanabe-Shibuya, P Miyazato… - Frontiers in …, 2020 - frontiersin.org
T cells infected with human T-cell leukemia virus type 1 (HTLV-1) transform into
malignant/leukemic cells and develop adult T-cell leukemia (ATL) after a long latency …

Advances in the treatment of HTLV-1-associated adult T-cell leukemia lymphoma

AA Phillips - Current Opinion in Virology, 2023 - Elsevier
Adult T-cell leukemia/lymphoma (ATLL) is an aggressive hematologic malignancy linked to
HTLV-1 infection, which is refractory to therapy. The precise mechanism of oncogenesis in …