[HTML][HTML] Regulatory network analysis reveals the oncogenesis roles of feed-forward loops and therapeutic target in T-cell acute lymphoblastic leukemia

M Xia, Q Zhang, M Luo, P Li, Y Wang, Q Lei… - BMC medical …, 2019 - Springer
Background T-cell acute lymphoblastic leukemia (T-ALL) is an aggressive hematological
malignancy. Aberrant expressed genes contribute to the development and progression of T …

HTLV-1-mediated dysregulation of the Wnt pathways: roles of Tax and HBZ

G Ma, J Yasunaga, J Fan, S Yanagawa, M Matsuoka - Retrovirology, 2014 - Springer
Human T cell leukemia virus type 1 (HTLV-1) is the causative agent of adult T-cell leukemia
(ATL). Dysregulations of cellular signaling pathways have been considered to be important …

Adult T-cell leukemia/lymphoma

M Matsuoka - Infectious Causes of Cancer: Targets for Intervention, 2000 - Springer
Adult T-cell leukemia (ATL) is a neoplasm of activated helper T lymphocytes, which was the
first human cancer found to be caused by a retrovirus, human T-cell lymphotropic virus type I …

[HTML][HTML] HTLV-1-mediated epigenetic pathway to adult T-cell leukemia–lymphoma

M Yamagishi, D Fujikawa, T Watanabe… - Frontiers in …, 2018 - frontiersin.org
Human T-cell leukemia virus type 1 (HTLV-1), the first reported human oncogenic retrovirus,
is the etiologic agent of highly aggressive, currently incurable diseases such as adult T-cell …

[HTML][HTML] Clinical characteristics, genetic alterations, and prognosis of adult T-cell leukemia/lymphoma: an 11-year multicenter retrospective study in China

L Luo, Y Chen, Z Wu, Y Huang, L Lu, J Li… - American Journal of …, 2024 - ncbi.nlm.nih.gov
Adult T-cell leukemia/lymphoma (ATLL) is an aggressive malignancy with a poor prognosis,
and there is little data available from the Chinese population. This retrospective study …

[HTML][HTML] Diagnostic approaches and established treatments for adult T cell leukemia lymphoma

K Tsukasaki, A Marçais, R Nasr, K Kato… - Frontiers in …, 2020 - frontiersin.org
Adult T-cell leukemia-lymphoma (ATL) is a distinct mature T-cell malignancy caused by
human T-cell leukemia/lymphotropic virus type I (HTLV-1) endemic in some areas in the …

Adult T-cell leukemia: molecular basis for clonal expansion and transformation of HTLV-1–infected T cells

T Watanabe - Blood, The Journal of the American Society of …, 2017 - ashpublications.org
Adult T-cell leukemia (ATL) is an aggressive T-cell malignancy caused by human T-cell
leukemia virus type 1 (HTLV-1) that develops through a multistep carcinogenesis process …

Genetic alterations in adult T‐cell leukemia/lymphoma

Y Kogure, K Kataoka - Cancer science, 2017 - Wiley Online Library
Adult T‐cell leukemia/lymphoma (ATL) is a peripheral T‐cell neoplasm with a dismal
prognosis. It is caused by human T‐cell leukemia virus type‐1 (HTLV‐1) retrovirus. A long …

[HTML][HTML] Future perspectives on drug targeting in adult T cell leukemia-lymphoma

F Marino-Merlo, A Mastino, S Grelli… - Frontiers in …, 2018 - frontiersin.org
Human T cell leukemia virus type 1 (HTLV-1) is the etiological agent of adult T cell
leukemia/lymphoma (ATL), HTLV-1 associated myelopathy (HAM/TSP), and of a number of …

[HTML][HTML] Regulation of human T-cell leukemia virus type 1 antisense promoter by myocyte enhancer factor-2C in the context of adult T-cell leukemia and lymphoma

KK Madugula, J Joseph, C DeMarino, R Ginwala… - …, 2022 - ncbi.nlm.nih.gov
Adult T-cell leukemia and lymphoma (ATLL) is an intractable T-cell neoplasia caused by a
retrovirus, namely human T-cell leukemia virus type 1 (HTLV-1). Patients suffering from …