The protein Talin1 encoded by the TLN1 gene is a focal adhesion-related protein that binds
to various cytoskeletal proteins and plays an important role in cell adhesion and movement …

Objectives Adult T‐cell leukemia/lymphoma (ATL) is an intractable T‐cell malignancy
caused by long‐term infection with human T‐cell leukemia virus type‐1 (HTLV‐1). While …

T-cell acute lymphoblastic leukemia (T-ALL) is an aggressive hematological malignancy.
The understanding of its gene expression regulation and molecular mechanisms still …

Premalignant clonal expansion of human T-cell leukemia virus type-1 (HTLV-1)–infected
cells occurs before viral carcinogenesis. Here we characterize premalignant cells and the …

The pediatric T cell acute lymphoblastic leukemia (T-ALL) still remains a cancer with worst
prognosis for high recurrence. Massive studies were conducted for the leukemia relapse …

Human T-cell leukemia virus type 1 (HTLV-1) establishes persistent infection in vivo in two
distinct ways: de novo infection and clonal proliferation of infected cells. Two viral genes …

Adult T-cell leukemia/lymphoma (ATLL) is a peripheral T-cell neoplasm with an extremely
poor prognosis. Maintaining ATLL cells in vitro is difficult and little is known about how they …

Adult T‐cell leukemia‐lymphoma (ATL) is caused by human T‐cell leukemia virus type 1
(HTLV‐1) infection. Among HTLV‐1 encoded genes, HTLV‐1 bZIP factor (HBZ) and tax are …

Peripheral T‐cell lymphoma (PTCL) is a heterogeneous entity generally with a poor
prognosis. Recent genomic analyses have characterized genomic alterations and described …

The main mechanisms of interaction between Human T‐lymphotropic virus type 1 (HTLV‐1)
and its hosts in the manifestation of the related disease including HTLV‐1 associated …