Since the ligand for the death factor CD95 (CD95L) was identified almost a decade ago, it
has been established that this molecule (CD95L, FasL, Apo-1L, CD178, TNFSF6, APT1LG1) …

The CD95 ligand is involved as a death factor in the regulation of activation-induced cell
death, establishment of immune privilege and tumor cell survival. In addition, CD95L may …

CD95 is a pre-ligand-associated transmembrane (TM) receptor. The interaction with its
ligand CD95L brings to a next level its aggregation and triggers different signaling …

Although CD95L (also known as FasL) is still predominantly considered as a death ligand
that induces apoptosis in infected and transformed cells, substantial evidence indicate that it …

CD95/CD95L mediated apoptosis is an important mechanism of immune homeostasis. It is
instrumental for termination of an immune response and mainly be involved in peripheral …

The TNF receptor superfamily member CD95 (Fas, APO-1, TNFRSF6) is known as the
prototypic death receptor in and outside the immune system. In fact, many mechanisms …

CD95 (also known as Fas) is the prototype of death receptors; however, evidence suggests
that this receptor mainly implements non-apoptotic signaling pathways such as NF-κB …

Endothelial cells lining new blood vessels that develop during inflammatory disorders or
cancers act as doors that either allow or block access to the tumor or inflamed organ. Recent …

Abstract CD95 (Apo1/Fas) has been originally identified as the target of cell death-inducing
antibodies. The recognition of CD95 as an apoptosis-triggering receptor represents one of …

CD95 and CD95 ligand (CD95L) are critical molecules of the immune system. They play an
important role in regulating T cell apoptosis. The membrane form of CD95L can be cleaved …