Cerebral blood flow is known to increase in response to hypoxia and to decrease with
hypocapnia. It is not known, however, whether these responses are altered in high‐altitude …

Aim: Acute hypobaric hypoxia is well known to alter brain circulation and to cause
neuropsychological impairment. However, very few studies have examined the regional …

New Findings What is the central question of this study? Recently, the heterogeneity of the
cerebral arterial circulation has been argued. Orthostatic tolerance may be associated with …

We examined changes in the blood flow velocity of brain stem artery (BSA) and middle
cerebral artery (MCA) in response to hypercapnic, normocapnic and hypocapnic …

To assess the effect of brain blood flow on hypoxic ventilatory response, we measured
arterial and internal jugular venous blood gases and ventilation simultaneously and …

Materials and Methods Macacus monkeys weighing from 3 to 6 kg. were used. Animals were
subdivided into two groups, acute and chronic. Each animal was anesthetized with …

This study examined the effect of high, normal, and uncontrolled end-tidal Pco2 (PetCO2) on
the ventilatory, peak cerebral blood flow velocity (V̄ p), and mean arterial blood pressure …

Cerebral blood flow increases at high altitude, but the mechanism of the increase and its
role in adaptation to high altitude are unclear. We hypothesized that the hypoxemia at high …

The influence of marked arterial hypoxia combined with unilateral carotid artery clamping
upon regional cortical metabolites and blood flow was studied in the rat brain. When the …

New Findings What is the central question of this study? Hypoxia associated with ascent to
high altitude may threaten cerebral oxygen delivery. We sought to determine whether there …