Purpose Drug development in chronic obstructive pulmonary disease (COPD) has been
characterised by unacceptably high failure rates. In addition to the poor sensitivity in forced …

Background: Demographic and disease characteristics have been associated with the risk of
chronic obstructive pulmonary disease (COPD) exacerbations. Using previously collected …

Purpose Prediction models for exacerbations in patients with chronic obstructive pulmonary
disease (COPD) are scarce. Our aim was to develop and validate a new model to predict …

Background Frequent exacerbations induce a high burden to Chronic Obstructive
Pulmonary Disease (COPD). We investigated the course of exacerbations in the published …

Background Lung function, measured as forced expiratory volume in one second (FEV1),
and exacerbations are two endpoints evaluated in chronic obstructive pulmonary disease …

Introduction Clinical studies demonstrate an accelerated decline in lung function in patients
with moderate chronic obstructive pulmonary disease (COPD)(Global Initiative for Chronic …

Personalised medicine aims to tailor medical decisions to the individual patient. A possible
approach is to stratify patients according to the risk of adverse outcomes such as …

The concept of the minimal clinically important difference (MCID) is intended to provide a
measure of relevance for a statistically applied in patients with COPD. Clinically important …

BACKGROUND: With increasing health care costs that have outpaced those of other
industries, payers of health care are moving from a fee-for-service payment model to one in …

Purpose The aims of this study were to develop a scoring model that predicts the effects of
withdrawing inhaled corticosteroids (ICSs) from triple therapy and to examine its adaptability …