Human aging is accompanied by both vascular and cognitive changes. Although arteries
throughout the body are known to become stiffer with age, this vessel hardening is believed …

Exercise is associated with higher cognitive function and is a promising intervention to
reduce the risk of dementia. With advancing age, there are changes in the vasculature that …

The mechanisms by which aerobic fitness confers beneficial effects on cognition with aging
are unclear but may involve cerebrovascular adaptations. In a cross-sectional study of …

The process of aging includes changes in cellular biology that affect local interactions
between cells and their environments and eventually propagate to systemic levels. In the …

Derangements in cerebrovascular structure and function can impair cognitive performance
throughout ageing and in cardiometabolic disease states, thus increasing dementia risk …

The brain's vasculature is likely to be subjected to the same age-related physiological and
anatomical changes affecting the rest of the cardiovascular system. Since aerobic fitness is …

Single lifestyle factors affect brain biomarkers and cognition. Here, we addressed the
covariance of various lifestyle elements and investigated their impact on positron emission …

Studies of the effects of physical fitness on cognition suggest that exercise can improve
cognitive abilities in healthy older adults, as well as delay the onset of age-related cognitive …

Alzheimer disease (AD) and cerebrovascular disease often coexist with advanced age.
Mounting evidence indicates that the presence of vascular disease and its risk factors …

Advanced age is the major risk factor for dementia including Alzheimer's disease. The
clinical effects of recently developed anti-amyloid therapy for Alzheimer's disease were …