For many decades, psychiatric treatment has been primarily guided by two major paradigms
of psychopathology: a neurochemical paradigm leading to the development of medications …

Major depression (MD) is characterized by the presence of depressed mood and/or
anhedonia, as well as a number of somatic, vegetative, and psychological symptoms. 1 It is …

Abstract Research of Deep Brain Stimulation as a putative treatment for resistant psychiatric
disorders might very well lead to the most significant development in clinical psychiatry of …

Despite best practices for the management of major depression with medications and
psychotherapy, many patients do not fully recover and need other treatment options …

Depression is one of the most disabling conditions in the world. In many cases patients
continue to suffer with depressive disorders despite a series of adequate trials of medication …

The use of neuromodulation as a treatment for major depressive disorder (MDD) has
recently attracted renewed interest due to development of other non-pharmacological …

Objective: The aim of this paper was to review the development of repetitive transcranial
magnetic stimulation (rTMS), magnetic seizure therapy (MST), vagal nerve stimulation …

Depression is the most prevalent debilitating mental illness; it is characterized as a disorder
of mood, cognitive function, and neurovegetative function. About one in ten individuals …

Drugs and psychotherapy are inadequate for relieving depressive symptoms in a substantial
portion of severely depressed patients. In that patient group, neurostimulation techniques …

Abstract Treatment‐resistant depression continues to pose a major medical challenge, as up
to one‐third of patients with major depressive disorder fail to have an adequate response to …