[PDF][PDF] Integrated lncRNA function upon genomic and epigenomic regulation
Although some long noncoding (lnc) RNAs are known since the 1950s, the past 25 years
have uncovered myriad lncRNAs with diverse sequences, structures, and functions. The …
have uncovered myriad lncRNAs with diverse sequences, structures, and functions. The …
A CRISPR knockout screen identifies SETDB1-target retroelement silencing factors in embryonic stem cells
In mouse embryonic stem cells (mESCs), the expression of provirus and endogenous
retroelements is epigenetically repressed. Although many cellular factors involved in …
retroelements is epigenetically repressed. Although many cellular factors involved in …
[HTML][HTML] Exosomal non-coding RNAs-mediated crosstalk in the tumor microenvironment
Q Chen, Y Li, Y Liu, W Xu, X Zhu - Frontiers in cell and developmental …, 2021 - frontiersin.org
Exosomes are secreted by different types of cells in tumor microenvironment (TME) and
participate in multiple biological processes of tumors. Non-coding RNAs (ncRNAs) …
participate in multiple biological processes of tumors. Non-coding RNAs (ncRNAs) …
Long noncoding RNAs in mouse embryonic stem cell pluripotency and differentiation
The transcriptional networks that regulate embryonic stem (ES) cell pluripotency and lineage
specification are the subject of considerable attention. To date such studies have focused …
specification are the subject of considerable attention. To date such studies have focused …
[PDF][PDF] Single-cell transcriptome analysis reveals dynamic changes in lncRNA expression during reprogramming
Cellular reprogramming highlights the epigenetic plasticity of the somatic cell state. Long
noncoding RNAs (lncRNAs) have emerging roles in epigenetic regulation, but their potential …
noncoding RNAs (lncRNAs) have emerging roles in epigenetic regulation, but their potential …
Cis-and trans-acting lncRNAs in pluripotency and reprogramming
Highlights•Cis-and trans-acting lncRNAs are involved in stem cell pluripotency and
reprogramming.•lncRNA-mediated cis regulation of nearby transcription is a prevalent …
reprogramming.•lncRNA-mediated cis regulation of nearby transcription is a prevalent …
Long antisense non-coding RNAs function to direct epigenetic complexes that regulate transcription in human cells
KV Morris - Epigenetics, 2009 - Taylor & Francis
Epigenetic silencing of tumor suppressor gene promoters is one of the most common
observations found in cancer. Despite the plethora of observed epigenetically silenced …
observations found in cancer. Despite the plethora of observed epigenetically silenced …
Posttranscriptional gene regulation by long noncoding RNA
JH Yoon, K Abdelmohsen, M Gorospe - Journal of molecular biology, 2013 - Elsevier
Eukaryotic cells transcribe a vast number of noncoding RNA species. Among them, long
noncoding RNAs (lncRNAs) have been widely implicated in the regulation of gene …
noncoding RNAs (lncRNAs) have been widely implicated in the regulation of gene …
Enhancer RNAs: a class of long noncoding RNAs synthesized at enhancers
Recent studies have revealed that active enhancers are transcribed, producing a class of
noncoding RNAs called enhancer RNAs (eRNAs). eRNAs are distinct from long noncoding …
noncoding RNAs called enhancer RNAs (eRNAs). eRNAs are distinct from long noncoding …
Co-transcriptional gene regulation in eukaryotes and prokaryotes
M Shine, J Gordon, L Schärfen, D Zigackova… - … Reviews Molecular Cell …, 2024 - nature.com
Many steps of RNA processing occur during transcription by RNA polymerases. Co-
transcriptional activities are deemed commonplace in prokaryotes, in which the lack of …
transcriptional activities are deemed commonplace in prokaryotes, in which the lack of …