Abstract Nucleotides, eg, adenosine‐5′‐triphosphate (ATP), can be released into the
extracellular space under acute or chronic inflammatory conditions and have been shown to …

While acute inflammation is widely accepted as an important response mechanism of cells
against tissue injury, sustained inflammatory processes are increasingly recognized as one …

Different studies have confirmed that P2X purinergic receptors play a key role in
inflammation. Activation of P2X purinergic receptors can release inflammatory cytokines and …

Under physiological conditions, adenosine triphosphate (ATP) is present at low levels in the
extracellular milieu, being massively released by stressed or dying cells. Once outside the …

Acute respiratory distress syndrome (ARDS) is a syndrome of acute respiratory failure due to
lung inflammation and noncardiogenic pulmonary edema that is familiar to all intensivists …

Acute respiratory distress syndrome (ARDS) is a clinical syndrome of non-cardiogenic
pulmonary oedema associated with bilateral pulmonary infiltrates, stiff lungs and refractory …

Many, potentially all, inflammatory and immune cells express purinergic receptors of the P1
and P2 type. In recent years, availability of molecular probes and, in some cases, specific …

Introduction Treatments for the acute respiratory distress syndrome (ARDS) are mainly
supportive, and ventilatory management represents a key approach in these patients …

Acute respiratory distress syndrome (ARDS) is an acute diffuse inflammatory lung injury
characterized by the damage of alveolar epithelial cells and pulmonary capillary endothelial …

Neuroinflammation limits tissue damage in response to pathogens or injury and promotes
repair. There are two stages of inflammation, initiation and resolution. P2X receptors are …