Seven P2X ion channel nucleotide receptor subtypes have been cloned and characterised.
P2X7 receptors (P2X7R) are unusual in that there are extra amino acids in the intracellular …

The acute respiratory distress syndrome (ARDS) is a clinical syndrome with primarily
supportive management options. Despite extensive basic and clinical investigations …

Over the last decade, the management of acute respiratory distress syndrome (ARDS) has
made considerable progress both regarding supportive and pharmacologic therapies. Lung …

ATP is stored in millimolar concentrations within the intracellular medium but may be
released to extracellular sites either through the damaged plasma membrane or by means …

Background Acute respiratory distress syndrome (ARDS) is a life-threatening form of
respiratory failure without a readily identifiable cause. The more objective method to …

Since their discovery in the 1970s, purinergic receptors have been shown to play key roles
in a wide variety of biologic systems and cell types. In the immune system, purinergic …

Acute respiratory distress syndrome (ARDS) is a frequently encountered clinical syndrome
associated with unacceptably high morbidity and mortality. 1 Since its first description in …

The acute respiratory distress syndrome (ARDS) is a severe lung disorder with a high
morbidity and mortality which affects all age groups. Despite active research with intense …

Acute Respiratory Distress Syndrome (ARDS) is a fulminant form of respiratory failure which
has diverse aetiology. Although the pathophysiology of the disease is understood in some …

The P2X4 receptor is an ATP-gated cation channel that is widely expressed in cells of the
immune system. It is able to form heterotrimers by combining with P2X2, P2X5, and/or P2X6 …