The relevance of cytokines for development of protective immunity and rational design of vaccines

JA Chabalgoity, A Baz, A Rial, S Grille - Cytokine & growth factor reviews, 2007 - Elsevier
Cytokines are key regulators of the immune system that shape innate and adaptive immune
responses. An adequate balance of the cytokine environment is critical to achieve protective …

The emerging role of avian cytokines as immunotherapeutics and vaccine adjuvants

LS Hilton, AGD Bean, JW Lowenthal - Veterinary Immunology and …, 2002 - Elsevier
The use of antibiotic feed additives and chemical antimicrobials in food production animals
is a double-edged sword. On one hand, it helps to prevent the outbreak of disease and …

Cytokines and their role as immunotherapeutics and vaccine Adjuvants: The emerging concepts

T Rahman, A Das, MH Abir, IH Nafiz, AR Mahmud… - Cytokine, 2023 - Elsevier
Cytokines are a protein family comprising interleukins, lymphokines, chemokines,
monokines and interferons. They are significant constituents of the immune system, and they …

T cell targeted immune enhancement yields effective T cell adjuvants

PH Naylor, JW Hadden - International immunopharmacology, 2003 - Elsevier
Given the critical role of cell-mediated immunity (CMI) in defense against attack from
pathogens that establish chronic infections, it has become abundantly clear that current …

Designer adjuvants for enhancing the efficacy of infectious disease and cancer vaccines based on suppression of regulatory T cell induction

KHG Mills - Immunology Letters, 2009 - Elsevier
Live attenuated or inactivated bacteria and viruses have formed the basis of many
successful vaccines, including those that have eliminated smallpox and have almost …

[HTML][HTML] Inflaming the CD8+ T cell response

JS Haring, VP Badovinac, JT Harty - Immunity, 2006 - cell.com
Although inflammatory cytokines induced by infection or vaccination with adjuvants have
long been known to stimulate optimal antigen-presenting cell function, recent evidence …

Mechanisms of vaccine adjuvant activity: initiation and regulation of immune responses by vaccine adjuvants

VEJC Schijns - Vaccine, 2003 - Elsevier
In the last century the use of vaccines has profoundly reduced morbidity and mortality of
infectious diseases within the human population and among veterinary species. In fact, the …

Cytokines as adjuvants for avian vaccines

M Asif, KA Jenkins, LS Hilton… - Immunology and cell …, 2004 - Wiley Online Library
The worldwide trend towards a reduced reliance on in‐feed antibiotics has increased the
pressure to develop alternative strategies to manage infectious diseases in poultry. With this …

Cytokine adjuvants for vaccine therapy of neoplastic and infectious disease

WK Decker, A Safdar - Cytokine & growth factor reviews, 2011 - Elsevier
Vaccination, the revolutionary prophylactic immunotherapy developed in the eighteenth
century, has become the most successful and cost-effective of medical remedies available to …

Avian cytokines—the natural approach to therapeutics

JW Lowenthal, B Lambrecht, TP van den Berg… - Developmental & …, 2000 - Elsevier
While the effective use of antibiotics for the control of human disease has saved countless
lives and has increased life expectancy over the past few decades, there are concerns …