Obesity, a low-grade inflammatory condition, represents a major risk factor for the
development of several pathologies including colorectal cancer (CRC). Although the …

Obesity is well accepted as crucial risk factor that plays a critical role in the initiation and
progression of colorectal cancer (CRC). More specifically, visceral adipose tissue (VAT) in …

Colorectal cancer (CRC) is a major health problem worldwide, with an estimated 1.9 million
new cases and 915,880 deaths in 2020 alone. The etiology of CRC is complex and involves …

Background Obesity is a chronic low-grade inflammatory disease that is generally
characterized by enhanced inflammation in obese adipose tissue (AT). Here, we …

Colorectal cancer (CRC) is a major life-threatening disease, being the third most common
cancer and a leading cause of death worldwide. Enhanced adiposity, particularly visceral …

Obesity, and the obesity-associated inflammation, represents a major risk factor for the
development of chronic diseases, including colorectal cancer (CRC). Dysfunctional visceral …

Obesity is a low-grade chronic inflammatory state representing an important risk factor for
colorectal cancer (CRC). Adipocytes strongly contribute to inflammation by producing …

Obesity is a major driving factor in the incidence, progression, and poor treatment response
in gastrointestinal cancers. Herein, we conducted a comprehensive analysis of the impact of …

Visceral obesity is characterized by increased risk of cardiovascular disease as well as
higher incidence of malignancies, including colorectal cancer (CRC), although the …

Obesity and obesity-driven cancer rates are continuing to rise worldwide. We hypothesize
that adipocyte–colonocyte interactions are a key driver of obesity-associated cancers. To …