The migration of vascular endothelial cells in vivo occurs in a fluid dynamic environment due
to blood flow, but the role of hemodynamic forces in cell migration is not yet completely …

Shear stress induces endothelial polarization and migration in the direction of flow
accompanied by extensive remodeling of the actin cytoskeleton. The GTPases RhoA, Rac1 …

Cyclic stretch is an artificial model of mechanical force loading, which induces the
reorientation of vascular endothelial cells and their stress fibers in a direction perpendicular …

Transmigration of leukocytes across the endothelial barrier is a tightly controlled process
involving multiple steps, including rolling adhesion, firm adhesion, and then penetration of …

The migration of endothelial cells (ECs) plays an important role in vascular remodeling and
regeneration. EC migration can be regulated by different mechanisms such as chemotaxis …

The vascular endothelium is exposed to an array of physical forces, including shear stress
via blood flow, contact with other cells such as neighboring endothelial cells and leukocytes …

Endothelial cells are constantly exposed to fluid shear stresses that regulate vascular
morphogenesis, homeostasis, and disease. The mechanical responses of endothelial cells …

Vascular endothelial cells (ECs) in vivo are subject to different flow conditions due to the
variation in vessel geometry. The aim of this study is to elucidate the effects of different flow …

The small GTPase Rho regulates the formation of actin stress fibers in adherent cells
through activation of its effector proteins Rho-kinase and mDia. We found in bovine aortic …

Shear stress, the tangential component of hemodynamic forces, plays an important role in
endothelial remodeling. In this study, we investigated the role of Rho family GTPases Cdc42 …