We have mapped and quantified mouse transcriptomes by deeply sequencing them and
recording how frequently each gene is represented in the sequence sample (RNA-Seq) …

The human transcriptome is so large, diverse, and dynamic that, even after a decade of
investigation by RNA sequencing (RNA-seq), we have yet to resolve its true dimensions …

RNA sequencing (RNA-seq) can be used to assemble spliced isoforms, quantify expressed
genes and provide a global profile of the transcriptome. However, the size and diversity of …

The functional complexity of the human transcriptome is not yet fully elucidated. We report a
high-throughput sequence of the human transcriptome from a human embryonic kidney and …

Our understanding of human biology and disease is ultimately dependent on a complete
understanding of the genome and its functions. The recent application of microarray and …

We compared quantitative RT-PCR (qRT-PCR), RNA-seq and capture sequencing
(CaptureSeq) in terms of their ability to assemble and quantify long noncoding RNAs and …

High-throughput mRNA sequencing (RNA-Seq) promises simultaneous transcript discovery
and abundance estimation,,. However, this would require algorithms that are not restricted …

Background RNA-seq is a powerful technique for identifying and quantifying transcription
and splicing events, both known and novel. However, given its recent development and the …

Global RNA studies have become central to understanding biological processes, but
methods such as microarrays and short-read sequencing are unable to describe an entire …

Single-cell RNA-seq mammalian transcriptome studies are at an early stage in uncovering
cell-to-cell variation in gene expression, transcript processing and editing, and regulatory …