In addition to being an advantageous model to investigate general molecular mechanisms
of organ formation, the tooth is a distinct target organ for peripheral nerve innervation. These …

The tooth, like many other organs, develops from both epithelial and mesenchymal tissues,
and has proven to be a valuable tool with which to investigate organ formation and …

Reciprocal interactions between epithelial and mesenchymal tissues play a fundamental
role in the morphogenesis of teeth and regulate all aspects of tooth development. Extensive …

Like many other organs, the tooth develops as a result of the epithelial‐mesenchymal
interactions. In addition, the tooth is a well‐defined peripheral target organ for sensory …

Timing and patterning of dental pulp innervation are strictly spatio-temporally regulated but it
is still not known how they are controlled at molecular level. We analyzed postnatal …

Mammalian tooth development has served as an excellent model system to investigate the
intricate, interactive mechanisms of patterning, morphogenesis and cytodifferentiation during …

Many vertebrate organs form through the sequential and reciprocal exchange of signaling
molecules between juxtaposed epithelial and mesenchymal tissues. We undertook a …

Sequential and reciprocal epithelial–mesenchymal interactions, essential throughout such
aspects of tooth morphogenesis as patterning, size and number of teeth, involves a well …

The purpose of this review is to discuss molecular factors influencing nerve growth to teeth.
The establishment of a sensory pulpal innervation occurs concurrently with tooth …

Teeth play essential roles in life. Their development relies on reciprocal interactions
between the ectoderm-derived dental epithelium and the underlying neural crest-originated …