Rifampicin as Adjunct to Colistin Therapy in the Treatment of Multidrug-Resistant Acinetobacter baumannii

M Al-Shaer, LH Nazer… - Annals of …, 2014 - journals.sagepub.com
Objective: To evaluate the available evidence regarding the efficacy and safety of rifampicin,
as adjunct to colistin, in the treatment of multidrug resistant Acinetobacter baumannii (MDR …

[HTML][HTML] Synergistic effect of colistin and rifampin against multidrug resistant Acinetobacter baumannii: a systematic review and meta-analysis

M Mohammadi, H Khayat, K Sayehmiri… - The open …, 2017 - ncbi.nlm.nih.gov
The existence of infections caused by multidrug resistant (MDR) Acinetobacter baumannii is
a growing problem because of the difficulty to treat them. We examined the published …

Synergistic Activity of Colistin and Rifampin Combination against Multidrug-Resistant Acinetobacter baumannii in an In Vitro Pharmacokinetic/Pharmacodynamic …

HJ Lee, PJ Bergen, JB Bulitta, B Tsuji… - Antimicrobial agents …, 2013 - Am Soc Microbiol
Combination therapy may be required for multidrug-resistant (MDR) Acinetobacter
baumannii. This study systematically investigated bacterial killing and emergence of colistin …

Multidrug-resistant Acinetobacter baumannii infections: Current evidence on treatment options and the role of pharmacokinetics/pharmacodynamics in dose …

SMS Lim, FB Sime, JA Roberts - International journal of antimicrobial …, 2019 - Elsevier
Acinetobacter baumannii remains a difficult-to-treat pathogen that poses a significant
challenge to clinicians and costs to the healthcare system. There is a lack of clinical efficacy …

Colistin Monotherapy versus Colistin plus Meropenem Combination Therapy for the Treatment of Multidrug-Resistant Acinetobacter baumannii Infection: A Meta …

C Huang, I Chen, T Tang - Journal of clinical medicine, 2022 - mdpi.com
(1) Introduction: Colistin combination therapy with other antibiotics is a way to enhance
colistin activity. The purpose of this meta-analysis was to compare the efficacy and safety of …

Colistin and Rifampicin Compared With Colistin Alone for the Treatment of Serious Infections Due to Extensively Drug-Resistant Acinetobacter baumannii: A …

E Durante-Mangoni, G Signoriello… - Clinical infectious …, 2013 - academic.oup.com
Background. Extensively drug-resistant (XDR) Acinetobacter baumannii may cause serious
infections in critically ill patients. Colistin often remains the only therapeutic option. Addition …

Colistin and rifampicin in the treatment of multidrug-resistant Acinetobacter baumannii infections

M Bassetti, E Repetto, E Righi, S Boni… - Journal of …, 2008 - academic.oup.com
Objectives The increased incidence of nosocomial infections by multidrug-resistant
organisms has motivated the re-introduction of colistin in combination with other …

Is there really no benefit to combination therapy with colistin?

JM Pogue, KS Kaye - Expert review of anti-infective therapy, 2013 - Taylor & Francis
Evaluation of: Colistin and Rifampicin compared with colistin alone for the treatment of
serious infections due to extensively drug-resistant Acinetobacter baumannii: a multicenter …

Efficacy and Safety of High Loading Dose of Colistin in Multidrug-Resistant Acinetobacter baumannii: A Prospective Cohort Study

W Katip, M Meechoui… - Journal of Intensive …, 2019 - journals.sagepub.com
Objectives: We aimed to assess the efficacy and safety of a high loading dose of colistin and
no loading dose of colistin to treat multidrug-resistant (MDR) Acinetobacter baumannii …

Combined colistin and rifampicin therapy for carbapenem-resistant Acinetobacter baumannii infections: clinical outcome and adverse events

N Petrosillo, MF Proietti… - Clinical …, 2005 - clinicalmicrobiologyandinfection …
We have observed previously that rifampicin is active in vitro against A. baumannii, and this
led us to investigate the potential therapeutic role of this antimicrobial agent in combination …