Background There is limited data on the impact of specific patient characteristics, tumor
subtypes or treatment interventions on survival in breast cancer LM. Methods A systematic …

Background Breast cancer (BC) is one of the solid tumors most commonly associated with
leptomeningeal disease (LMD). LMD carries a devastating prognosis; however, disease …

Background Leptomeningeal metastasis (LM) is one of the major problems in the
management of metastatic breast cancer; typically, LM has a devastating prognosis and …

Background Disease presentation, prognostic factors, and treatment patterns for patients
with breast cancer with leptomeningeal metastasis are not well characterized. In this study …

Leptomeningeal metastasis (LM) usually occurs late during the course of breast cancer. The
aim of this study was to characterize the clinical features and outcomes of LM based on …

The aim of the study was to define biological subtypes of breast cancer that have the
propensity to metastasize to the leptomeninges and to assess factors influencing survival …

In patients with human epidermal growth factor receptor 2 positive (HER2+) breast cancer,
leptomeningeal metastases (LM) are a rare but often a fatal clinical scenario. In this …

Background Leptomeningeal metastasis (LM) is a rare complication of metastatic breast
cancer (MBC), with high morbidity/mortality rates. Our study aimed to describe the largest-to …

Leptomeningeal metastasis (LM) in breast cancer patients confers a uniformly poor
prognosis and decreased quality of life. Treatment options are limited and often ineffective …

Clinical data supporting the best therapeutic approach in leptomeningeal disease (LMD;
also known as leptomeningeal metastases or leptomeningeal carcinomatosis) are lacking …