Bacterial acid stress response: From cellular changes to antibiotic tolerance and phenotypic heterogeneity

K Schumacher, S Brameyer, K Jung - Current Opinion in Microbiology, 2023 - Elsevier
Highlights•Bacteria have common and species-specific mechanisms to survive acid
stress.•Acid stress response and antibiotic tolerance are interconnected.•Acid stress …

Microbial mechanisms of tolerance to weak acid stress

NP Mira, MC Teixeira - Frontiers in microbiology, 2013 - frontiersin.org
Carboxylic acids are ubiquitous molecules found in microbial metabolic pathways and that
have been explored for a wide array of applications including food preservation (eg, acetic …

Understanding how microorganisms respond to acid pH is central to their control and successful exploitation

PA Lund, D De Biase, O Liran, O Scheler… - Frontiers in …, 2020 - frontiersin.org
Microbes from the three domains of life, Bacteria, Archaea, and Eukarya, share the need to
sense and respond to changes in the external and internal concentrations of protons. When …

Microbial response to acid stress: mechanisms and applications

N Guan, L Liu - Applied microbiology and biotechnology, 2020 - Springer
Microorganisms encounter acid stress during multiple bioprocesses. Microbial species have
therefore developed a variety of resistance mechanisms. The damage caused by acidic …

Sensing and adapting to acid stress

IR Booth, P Cash, C O'byrne - Antonie Van Leeuwenhoek, 2002 - Springer
Bacteria and archaea occupy a considerable diversity of niches that vary with respect to the
physical conditions. Survival and colonisation requires the capacity to sense, and adapt to …

Heterogeneity and evolutionary tunability of Escherichia coli resistance against extreme acid stress

S Van Riet, W Tadesse, J Mortier, S Schlegel… - Microbiology …, 2022 - Am Soc Microbiol
Since acidic environments often serve as an important line of defense against bacterial
pathogens, it is important to fully understand how the latter manage to mount and evolve …

Comparative Review of the Responses of Listeria monocytogenes and Escherichia coli to Low pH Stress

T Arcari, ML Feger, DN Guerreiro, J Wu, CP O'Byrne - Genes, 2020 - mdpi.com
Acidity is one of the principal physicochemical factors that influence the behavior of
microorganisms in any environment, and their response to it often determines their ability to …

Ribosome profiling reveals the fine-tuned response of Escherichia coli to mild and severe acid stress

K Schumacher, R Gelhausen, W Kion-Crosby… - Msystems, 2023 - Am Soc Microbiol
The ability to respond to acidic environments is crucial for neutralophilic bacteria.
Escherichia coli has a well-characterized regulatory network that triggers a multitude of …

Coping with low pH: molecular strategies in neutralophilic bacteria

P Lund, A Tramonti, D De Biase - FEMS microbiology reviews, 2014 - academic.oup.com
As part of their life cycle, neutralophilic bacteria are often exposed to varying environmental
stresses, among which fluctuations in pH are the most frequent. In particular, acid …

The acid adaptive tolerance response in Campylobacter jejuni induces a global response, as suggested by proteomics and microarrays

A Varsaki, C Murphy, A Barczynska… - Microbial …, 2015 - Wiley Online Library
C ampylobacter jejuni CI 120 is a natural isolate obtained during poultry processing and has
the ability to induce an acid tolerance response (ATR) to acid+ aerobic conditions in early …