High‐Fat Diet Promotes Adipogenesis in Offspring Female Rats Induced by Perinatal Exposure to 4‐Nonylphenol

H Zhang, W Ke, X Chen, Y Han, Y Xiong… - BioMed Research …, 2023 - Wiley Online Library
Background. Both high‐fat diet (HFD) and 4‐nonylphenol (4‐NP) could affect fat formation in
adipose tissue individually. We investigated whether HFD promote abnormal adipose tissue …

High-fat diet accelerate hepatic fatty acids synthesis in offspring male rats induced by perinatal exposure to nonylphenol

H Zhang, C Song, R Yan, H Cai, Y Zhou… - BMC Pharmacology and …, 2021 - Springer
Background Low dose of NP exposure can alter adipose tissue formation, and the intake of
high-fat diet (HFD) can also lead to the fatty liver disease. We investigated the combined …

Perinatal exposure to 4-nonylphenol affects adipogenesis in first and second generation rats offspring

H Zhang, W Xue, Y Li, Y Ma, Y Zhu, W Huo, B Xu… - Toxicology letters, 2014 - Elsevier
Abstract Maternal exposure to 4-nonylphenol (4-NP) during pregnancy was shown to alter
adipogenesis in rodents, yet whether the effects are restricted to 4-NP-exposed offspring …

The endocrine disruptor 4-nonylphenol promotes adipocyte differentiation and induces obesity in mice

C Hao, X Cheng, H Xia, X Ma - Cellular Physiology and Biochemistry, 2012 - karger.com
Abstract Background/Aim: The environmental obesogen hypothesis proposes that exposure
to endocrine disruptors during developmental “window” contributes to adipogenesis and the …

Perinatal exposure to 4-nonylphenol can affect fatty acid synthesis in the livers of F1 and F2 generation rats

H Zhang, W Xue, Y Zhu, W Huo, B Xu… - Toxicology Research, 2018 - academic.oup.com
Objective: To explore the effects of different dosages of 4-nonylphenol (4-NP) on the fatty
acid synthesis and estrogen receptor α (ERα) expression in the livers of F1 and F2 rats …

The adverse effect of 4-tert-octylphenol on fat metabolism in pregnant rats via regulation of lipogenic proteins

J Kim, EJ Kang, MN Park, JE Kim, SC Kim… - Environmental …, 2015 - Elsevier
Alkylphenols such as 4-tert-octylphenol (OP), nonylphenol, and bisphenol A are classified
as endocrine-disrupting chemicals (EDCs). Digestion and metabolism of food are controlled …

In utero and neonate exposure to nonylphenol develops hyperadrenalism and metabolic syndrome later in life. I. First generation rats (F1)

LL Chang, WSA Wun, PS Wang - Toxicology, 2012 - Elsevier
Nonylphenol (NP) is an endocrine disruptor (ENDR). It is a chemical associated with the
production and degradation of nonylphenol ethoxylates (NPE). NPE is widely used as …

Adipogenic effects of prenatal exposure to bisphenol S (BPS) in adult F1 male mice

YA Ahn, H Baek, M Choi, J Park, SJ Son, HJ Seo… - Science of The Total …, 2020 - Elsevier
Bisphenol S (BPS) has been increasingly used as a substitute for bisphenol A (BPA), a
known endocrine disruptor. Early-life exposure to BPA affects fetal development and the risk …

Prenatal high-fat diet combined with microplastic exposure induces liver injury via oxidative stress in male pups

MM Tiao, JM Sheen, IC Lin, M Khwepeya… - International Journal of …, 2023 - mdpi.com
Prenatal high-fat diet (HFD) or exposure to microplastics can affect the accumulation of liver
fat in offspring. We sought to determine the effects of maternal HFD intake and microplastic …

An inhibitor of 11-β hydroxysteroid dehydrogenase type 1 (PF915275) alleviates nonylphenol-induced hyperadrenalism and adiposity in rat and human cells

LL Chang, WSA Wun, PS Wang - BMC Pharmacology and Toxicology, 2018 - Springer
Background Nonylphenol (NP) is an environmental endocrine-disrupting chemical (EDC)
detected in human cord blood and milk. NP exposure in developmental periods results in …