Ursolic acid treats renal tubular epithelial cell damage induced by calcium oxalate monohydrate via inhibiting oxidative stress and inflammation

Z Jia, W Li, P Bian, L Yang, H Liu, D Pan, Z Dou - Bioengineered, 2021 - Taylor & Francis
Ursolic acid (UA) has been proved to have antioxidant and anti-inflammatory effects.
However, it is not clear whether it has a protective impact on kidney damage induced by …

[HTML][HTML] Ursolic acid improves diabetic nephropathy via suppression of oxidative stress and inflammation in streptozotocin-induced rats

H Xu, X Wang, Y Cheng, J Zhao, Y Zhou, J Yang… - Biomedicine & …, 2018 - Elsevier
Inflammation plays a pivotal role in the pathogenesis of diabetic nephropathy (DN).
Overexpression of inflammatory chemokine and cytokines is involved in the development of …

[HTML][HTML] Renoprotective effects of ursolic acid on ischemia/reperfusion‑induced acute kidney injury through oxidative stress, inflammation and the inhibition of STAT3 …

J Peng, X Ren, T Lan, Y Chen… - Molecular Medicine …, 2016 - spandidos-publications.com
Ursolic acid, a pentacyclic triterpene compound with low toxicity and easy availability, has a
variety of biological activities, including antitumor, antioxidant, antihepatitis, anti …

Ursolic acid ameliorates carbon tetrachloride-induced oxidative DNA damage and inflammation in mouse kidney by inhibiting the STAT3 and NF-κB activities

JQ Ma, J Ding, ZH Xiao, CM Liu - International Immunopharmacology, 2014 - Elsevier
Ursolic acid (UA), a common pentacyclic triterpenoid compound, has been reported to have
many benefits and medicinal properties. However, its protective effects against carbon …

Hydroxycitric acid inhibits renal calcium oxalate deposition by reducing oxidative stress and inflammation

X Liu, P Yuan, X Sun, Z Chen - Current molecular medicine, 2020 - ingentaconnect.com
Objective: The study aimed to evaluate the preventive effects of hydroxycitric acid (HCA) for
stone formation in the glyoxylate-induced mouse model. Materials and Methods: Male …

[HTML][HTML] Oral supplementation with ursolic acid ameliorates sepsis-induced acute kidney injury in a mouse model by inhibiting oxidative stress and inflammatory …

Z Zhang, H Zhang, R Chen… - Molecular medicine …, 2018 - spandidos-publications.com
Ursolic acid (UA) as a multiple bioactive native compound has recently been demonstrated
to treat sepsis in animal models. However, the beneficial effects of UA in sepsis‑induced …

[HTML][HTML] Acteoside alleviates UUO-induced inflammation and fibrosis by regulating the HMGN1/TLR4/TREM1 signaling pathway

Y Mao, J Yu, J Da, F Yu, Y Zha - PeerJ, 2023 - peerj.com
ABSTRACT Purpose. Acteoside (Act), a phenylethanoid compound that was first isolated
from mullein, has been widely used for the investigation of anti-inflammatory and antifibrotic …

[HTML][HTML] Oral hydrogen-rich water alleviates oxalate-induced kidney injury by suppressing oxidative stress, inflammation, and fibrosis

Y Si, L Liu, J Cheng, T Zhao, Q Zhou, J Yu… - Frontiers in …, 2021 - frontiersin.org
Objective: To explore the theraputic effects and potential mechanisms of hydrogen-rich
water (HRW) against oxalate-induced kidney injury. Methods: The mouse model of Calcium …

KS370G, a caffeamide derivative, attenuates unilateral ureteral obstruction-induced renal fibrosis by the reduction of inflammation and oxidative stress in mice

ST Chuang, YH Kuo, MJ Su - European Journal of Pharmacology, 2015 - Elsevier
Unilateral ureteral obstruction (UUO) is an established animal model used to study renal
nephropathy. Caffeic acid phenethyl ester, a natural phenolic compound, possesses …

Hyperoside ameliorates renal tubular oxidative damage and calcium oxalate deposition in rats through AMPK/Nrf2 Signaling Axis

H Tian, Q Liang, Z Shi, H Zhao - Journal of the Renin …, 2023 - journals.sagepub.com
Background. Nephrolithiasis is a common disease that seriously affects the health and life
quality of patients. Despite the reported effect of hyperoside (Hyp) against nephrolithiasis …