Nanotechnology-based radiation therapy to cure cancer and the challenges in its clinical applications
Radiation therapy against cancer frequently fails to attain the desired outcomes because of
several restricting aspects. Radiation therapy is not a targeted antitumor treatment, and it …
several restricting aspects. Radiation therapy is not a targeted antitumor treatment, and it …
Multifunctional high-Z nanoradiosensitizers for multimodal synergistic cancer therapy
J Chen, H Dong, L Bai, L Li, S Chen, X Tian… - Journal of Materials …, 2022 - pubs.rsc.org
Radiotherapy (RT) is one of the most common and effective clinical therapies for malignant
tumors. However, there are several limitations that undermine the clinical efficacy of cancer …
tumors. However, there are several limitations that undermine the clinical efficacy of cancer …
Potential of natural products as radioprotectors and radiosensitizers: Opportunities and challenges
J Yi, J Zhu, C Zhao, Q Kang, X Zhang, K Suo, N Cao… - Food & Function, 2021 - pubs.rsc.org
Natural products can be used as natural radiosensitizers and radioprotectors, showing
promising effects in cancer treatments in combination with radiotherapy, while reducing …
promising effects in cancer treatments in combination with radiotherapy, while reducing …
Antioxidant nanomedicine significantly enhances the survival benefit of radiation cancer therapy by mitigating oxidative stress‐induced side effects
Oxidative stress‐induced off‐target effects limit the therapeutic window of radiation therapy.
Although many antioxidants have been evaluated as radioprotective agents, none of them …
Although many antioxidants have been evaluated as radioprotective agents, none of them …
Research progress on nano-sensitizers for enhancing the effects of radiotherapy
Y Zhang, X Han, Y Liu, S Wang, X Han, C Cheng - Materials Advances, 2022 - pubs.rsc.org
Radiotherapy (RT) is local control of tumors using radiation, including external irradiation
(EBRT) and internal irradiation (RIT). Cancer radiotherapy based on external beams is a …
(EBRT) and internal irradiation (RIT). Cancer radiotherapy based on external beams is a …
The refined application and evolution of nanotechnology in enhancing radiosensitivity during radiotherapy: transitioning from gold nanoparticles to multifunctional …
A Zhang, L Gao - International Journal of Nanomedicine, 2023 - Taylor & Francis
Radiotherapy is a pivotal method for treating malignant tumors, and enhancing the
therapeutic gain ratio of radiotherapy through physical techniques is the direction of modern …
therapeutic gain ratio of radiotherapy through physical techniques is the direction of modern …
The promise of nanoparticles-based radiotherapy in cancer treatment
Simple Summary Radiotherapy (RT) is used worldwide as a gold standard treatment
approach for cancer management. However, the RT treatment modality contains limitations …
approach for cancer management. However, the RT treatment modality contains limitations …
Hafnium oxide nanoparticles coated ATR inhibitor to enhance the radiotherapy and potentiate antitumor immune response
R Liu, C Zhang, X Wu, C Wang, M Zhao, C Ji… - Chemical Engineering …, 2023 - Elsevier
Nanomaterials as radioenhancer have been widely studied, which exhibits huge
advantages in tumor radiotherapy. However, DNA damage repair in tumor cells leads to …
advantages in tumor radiotherapy. However, DNA damage repair in tumor cells leads to …
Augmenting the therapeutic window of radiotherapy: A perspective on molecularly targeted therapies and nanomaterials
Radiation therapy is a cornerstone of modern cancer therapy alongside surgery,
chemotherapy, and immunotherapy, with over half of all cancer patients receiving radiation …
chemotherapy, and immunotherapy, with over half of all cancer patients receiving radiation …
Chemical and biological basis for development of novel radioprotective drugs for cancer therapy
R Checker, RS Patwardhan, S Jayakumar… - Free Radical …, 2021 - Taylor & Francis
Ionizing radiation (IR) causes chemical changes in biological systems through direct
interaction with the macromolecules or by causing radiolysis of water. This property of IR is …
interaction with the macromolecules or by causing radiolysis of water. This property of IR is …