Anti‐retroviral drug resistance‐associated mutations among non‐subtype B HIV‐1‐infected Kenyan children with treatment failure

R Lwembe, W Ochieng, A Panikulam… - Journal of medical …, 2007 - Wiley Online Library
Recently increased availability of anti‐retroviral therapy (ART) has mitigated HIV‐1/AIDS
prognoses especially in resource poor settings. The emergence of ART resistance …

Antiretroviral drug resistance profiles and response to second-line therapy among HIV type 1-infected Ugandan children

V Musiime, E Kaudha, J Kayiwa, G Mirembe… - AIDS research and …, 2013 - liebertpub.com
We sought to determine the pattern of resistance-associated mutations (RAMs) among HIV-1-
infected children failing first-line antiretroviral therapy (ART) and ascertain their response to …

Emergence of drug resistance in HIV-1 subtype C infected children failing the South African national antiretroviral roll-out program

CL Wallis, L Erasmus, S Varughese… - The Pediatric …, 2009 - journals.lww.com
HIV-1 drug resistance patterns in 41 children failing antiretroviral therapy in South Africa
were examined. Resistance mutation profiles were similar to adults published from the …

Prevalence of genotypic resistance to antiretroviral drugs in treatment-naive youths infected with diverse HIV type 1 subtypes and recombinant forms in Dar es Salaam …

F Mosha, W Urassa, S Aboud, E Lyamuya… - AIDS research and …, 2011 - liebertpub.com
As human immunodeficiency virus (HIV) diversity may have an impact on both vaccine
efficacy and drug resistance, it is important to have knowledge of circulating genetic variants …

HIV type 1 subtype C drug resistance among pediatric and adult South African patients failing antiretroviral therapy

V Pillay, C Pillay, R Kantor, F Venter… - AIDS research and …, 2008 - liebertpub.com
The emergence of HIV drug resistance is a major obstacle to effective antiretroviral (ARV)
treatments. This study examined the drug resistance profiles among South African patients …

HIV drug resistance among children initiating first-line antiretroviral treatment in Uganda

C Kityo, KCE Sigaloff, TS Boender… - AIDS research and …, 2016 - liebertpub.com
Background: There are limited data on primary human immunodeficiency virus drug
resistance (HIVDR) in pediatric populations. This study aimed to assess the prevalence of …

Reverse transcriptase genotypes in pediatric patients failing initial antiretroviral therapy in Gaborone, Botswana

M Tolle, L Howard, B Kirk, A Gomila… - Journal of the …, 2012 - journals.sagepub.com
Background Limited data are available on patterns of resistance mutations in pediatric
patients in southern Africa, where HIV-1 subtype C (HIV-1C) predominates. Methods …

Drug resistance in children at virological failure in a rural KwaZulu-Natal, South Africa, cohort

S Pillay, RM Bland, RJ Lessells, J Manasa… - AIDS research and …, 2014 - Springer
Background Better understanding of drug resistance patterns in HIV-infected children on
antiretroviral therapy (ART) is required to inform public health policies in high prevalence …

Early virologic failure and the development of antiretroviral drug resistance mutations in HIV-infected Ugandan children

TD Ruel, MR Kamya, P Li, W Pasutti… - JAIDS Journal of …, 2011 - journals.lww.com
Background: Without virologic testing, HIV-infected African children starting antiretroviral
(ARV) therapy are at risk for undetected virologic failure and the development of ARV …

high rates of thymidine analogue mutations and dual-class resistance among HIV-infected Ugandan children failing first-line antiretroviral therapy

KCE Sigaloff, J Kayiwa, V Musiime… - AIDS research and …, 2013 - liebertpub.com
HIV-infected children are at high risk of acquiring drug-resistant viruses, which is of
particular concern in settings where antiretroviral drug options are limited. We aimed to …