Dietary selenium variation-induced oxidative stress modulates CDC2/cyclin B1 expression and apoptosis of germ cells in mice testis

N Kaushal, MP Bansal - The Journal of nutritional biochemistry, 2007 - Elsevier
Oxidative stress has been linked with apoptosis in germ cells and with male infertility.
However, the molecular mechanism of oxidative-stress-mediated apoptosis in germ cells …

Inhibition of CDC2/Cyclin B1 in response to selenium-induced oxidative stress during spermatogenesis: potential role of Cdc25c and p21

N Kaushal, MP Bansal - Molecular and cellular biochemistry, 2007 - Springer
Various cell cycle regulators control and coordinate the process of cell cycle. Because of the
crucial involvement of CDC2, Cyclin B1, Cdc25c, and p21 in cell cycle regulation, the …

Selenium variation induced oxidative stress regulates p53 dependent germ cell apoptosis: plausible involvement of HSP70-2

N Kaushal, MP Bansal - European journal of nutrition, 2009 - Springer
Background Selenium at altered concentration causes abnormal spermatogenesis and male
infertility. However, the exact mechanism behind this is still unexplored. Aims It was aimed to …

Diminished reproductive potential of male mice in response to selenium‐induced oxidative stress: Involvement of HSP70, HSP70‐2, and MSJ‐1

N Kaushal, MP Bansal - Journal of biochemical and molecular …, 2009 - Wiley Online Library
The oxidative stress imposed by nutritional variations in selenium (Se) has plausible role in
reproductive toxicology and affects the reproductive potential. Also, the expression of heat …

Effect of selenium-induced oxidative stress on the cell kinetics in testis and reproductive ability of male mice

P Kaur, MP Bansal - Nutrition, 2005 - Elsevier
OBJECTIVE: The present study evaluated the role of experimental oxidative stress (induced
by feeding diets with different concentrations of selenium [Se], a trace nutrient and potent …

Both selenium deficiency and excess impair male reproductive system via inducing oxidative stress-activated PI3K/AKT-mediated apoptosis and cell proliferation …

Z Xu, M Liu, QJ Niu, YX Huang, L Zhao, XG Lei… - Free Radical Biology …, 2023 - Elsevier
Selenium (Se) deficiency or excess impairs testicular development and spermatogenesis,
while the underlying mechanisms in this regard remain unclear. This study was designed to …

Dietary selenium excess affected spermatogenesis via DNA damage and telomere-related cell senescence and apoptosis in mice

Y Zhang, J Liu, X Li, G Zhou, Y Sang, M Zhang… - Food and Chemical …, 2023 - Elsevier
Selenium (Se) is a vital microelement for spermatogenesis and male fertility. The aim of this
study was to investigate the effects of Se on the male reproductive function and possible …

Apoptosis induced by modulation in selenium status involves p38 MAPK and ROS: implications in spermatogenesis

P Ranawat, MP Bansal - Molecular and cellular biochemistry, 2009 - Springer
Selenium has been linked to cell survival and apoptosis. Apoptosis plays an important role
in spermatogenesis. Evidence suggests that reactive oxygen species induce apoptotic …

Effect of experimental oxidative stress on steroidogenesis and DNA damage in mouse testis

P Kaur, MP Bansal - Journal of Biomedical Science, 2004 - Springer
The objective of the present study was to evaluate the effect of oxidative stress induced by
feeding various levels of selenium on steroidogenesis and DNA damage in mouse testes …

Influence of selenium induced oxidative stress on spermatogenesis and lactate dehydrogenase-X in mice testis.

P Kaur, MP Bansal - Asian journal of andrology, 2004 - europepmc.org
Aim To evaluate the effect of oxidative stress on the spermatogenesis and lactate
dehydrogenase-X (LDH-X) activity in mouse testis. Methods For creating different levels of …