[PDF][PDF] An ancient fecundability-associated polymorphism switches a repressor into an enhancer of endometrial TAP2 expression
Variation in female reproductive traits, such as fertility, fecundity, and fecundability, is
heritable in humans, but identifying and functionally characterizing genetic variants …
heritable in humans, but identifying and functionally characterizing genetic variants …
[HTML][HTML] Expression Quantitative Trait Locus Mapping Studies in Mid-secretory Phase Endometrial Cells Identifies HLA-F and TAP2 as Fecundability-Associated …
CK Burrows, G Kosova, C Herman, K Patterson… - PLoS …, 2016 - journals.plos.org
Fertility traits in humans are heritable, however, little is known about the genes that influence
reproductive outcomes or the genetic variants that contribute to differences in these traits …
reproductive outcomes or the genetic variants that contribute to differences in these traits …
[PDF][PDF] An ancient fecundability-associated polymorphism creates a GATA2 binding site in a distal enhancer of HLA-F
Variation in female reproductive traits, such as fertility, fecundity, and fecundability, are
heritable in humans, but identifying and functionally characterizing genetic variants …
heritable in humans, but identifying and functionally characterizing genetic variants …
[PDF][PDF] Genome-wide association study identifies candidate genes for male fertility traits in humans
Despite the fact that hundreds of genes are known to affect fertility in animal models,
relatively little is known about genes that influence natural fertility in humans. To broadly …
relatively little is known about genes that influence natural fertility in humans. To broadly …
Gamete-level immunogenetic incompatibility in humans–towards deeper understanding of fertilization and infertility?
Human leukocyte antigen (HLA) immune genes play an important role in partner selection,
but it has remained unclear if nonrandom pairing with respect to parental HLA genes could …
but it has remained unclear if nonrandom pairing with respect to parental HLA genes could …
Genome-wide association studies on endometriosis and endometriosis-related infertility
G Galarneau, P Fontanillas, Celmatix Research Team… - BioRxiv, 2018 - biorxiv.org
Endometriosis affects∼ 10% of women of reproductive age. It is characterized by the growth
of endometrial-like tissue outside the uterus and is frequently associated with severe pain …
of endometrial-like tissue outside the uterus and is frequently associated with severe pain …
The evolution of menstruation: a new model for genetic assimilation: explaining molecular origins of maternal responses to fetal invasiveness
Why do humans menstruate while most mammals do not? Here, we present our answer to
this long‐debated question, arguing that (i) menstruation occurs as a mechanistic …
this long‐debated question, arguing that (i) menstruation occurs as a mechanistic …
[HTML][HTML] Genetic variation and reproductive timing: African American women from the Population Architecture using Genomics and Epidemiology (PAGE) Study
KL Spencer, J Malinowski, CL Carty, N Franceschini… - PloS one, 2013 - journals.plos.org
Age at menarche (AM) and age at natural menopause (ANM) define the boundaries of the
reproductive lifespan in women. Their timing is associated with various diseases, including …
reproductive lifespan in women. Their timing is associated with various diseases, including …
TAp63 as a guardian of female germ line integrity
W Xian, F McKeon - Nature Structural & Molecular Biology, 2018 - nature.com
TAp63 as a guardian of female germ line integrity | Nature Structural & Molecular Biology Skip to
main content Thank you for visiting nature.com. You are using a browser version with limited …
main content Thank you for visiting nature.com. You are using a browser version with limited …
The pregnancy pickle: evolved immune compensation due to pregnancy underlies sex differences in human diseases
We hypothesize that, ancestrally, sex-specific immune modulation evolved to facilitate
survival of the pregnant person in the presence of an invasive placenta and an …
survival of the pregnant person in the presence of an invasive placenta and an …