Genetics of female infertility in humans
B Bhagavath, LC Layman - Elsevier Inc., 2014 - books.google.com
32.4 CONCLUSION Increasingly, additional genes are being identified to cause the most
severe forms of infertility in females. These findings have improved our understanding of …
severe forms of infertility in females. These findings have improved our understanding of …
The maternal-fetal interface of successful pregnancies and impact of fetal sex using single cell sequencing
The first trimester is a critical window of maternal-fetal communication for pregnancy.
Therefore, we characterized crosstalk in ongoing human pregnancies at 11-13 weeks …
Therefore, we characterized crosstalk in ongoing human pregnancies at 11-13 weeks …
[HTML][HTML] Selected heterozygosity at cis-regulatory sequences increases the expression homogeneity of a cell population in humans
Background Examples of heterozygote advantage in humans are scarce and limited to
protein-coding sequences. Here, we attempt a genome-wide functional inference of …
protein-coding sequences. Here, we attempt a genome-wide functional inference of …
Genotyping TAP2 variants in North American Caucasians, Brazilians, and Africans
J Tang, DO Freedman, S Allen, E Karita, R Musonda… - Genes & …, 2001 - nature.com
The protein forms of transporter associated with antigen processing, subunit 2 (TAP2), differ
either by amino acid substitutions (Thr374Ala, Ile379Val, Ile467Val, Thr565Ala, Val577Met …
either by amino acid substitutions (Thr374Ala, Ile379Val, Ile467Val, Thr565Ala, Val577Met …
[HTML][HTML] The rs1127354 polymorphism in ITPA is associated with susceptibility to infertility
F Mollaahmadi, A Moini, RS Yazdi… - Cell Journal …, 2018 - ncbi.nlm.nih.gov
Objective Infertility is a common human disorder which is defined as the failure to conceive
for a period of 12 months without contraception. Many studies have shown that the outcome …
for a period of 12 months without contraception. Many studies have shown that the outcome …
[HTML][HTML] Allelic Imbalance in Regulation of ANRIL through Chromatin Interaction at 9p21 Endometriosis Risk Locus
H Nakaoka, A Gurumurthy, T Hayano, S Ahmadloo… - PLoS …, 2016 - journals.plos.org
Genome-wide association studies (GWASs) have discovered numerous single nucleotide
polymorphisms (SNPs) associated with human complex disorders. However, functional …
polymorphisms (SNPs) associated with human complex disorders. However, functional …
[HTML][HTML] Parental haplotype-specific single-cell transcriptomics reveal incomplete epigenetic reprogramming in human female germ cells
In contrast to mouse, human female germ cells develop asynchronously. Germ cells
transition to meiosis, erase genomic imprints, and reactivate the X chromosome. It is …
transition to meiosis, erase genomic imprints, and reactivate the X chromosome. It is …
Transformation of a transposon into a derived prolactin promoter with function during human pregnancy
Transposable elements (TEs) are known to provide DNA for host regulatory functions, but
the mechanisms underlying the transformation of TEs into cis-regulatory elements are …
the mechanisms underlying the transformation of TEs into cis-regulatory elements are …
Transgenerational paternal transmission of acquired traits: stress-induced modification of the sperm regulatory transcriptome and offspring phenotypes
Highlights•Recent evidence supports the paternal transgenerational transmission of
acquired traits.•Paternal stress had impacts on offspring behaviours and neuroendocrine …
acquired traits.•Paternal stress had impacts on offspring behaviours and neuroendocrine …
Genome-wide identification of regulatory elements in Sertoli cells
DM Maatouk, A Natarajan, Y Shibata, L Song… - …, 2017 - journals.biologists.com
A current goal of molecular biology is to identify transcriptional networks that regulate cell
differentiation. However, identifying functional gene regulatory elements has been …
differentiation. However, identifying functional gene regulatory elements has been …